Development of heterocyclic-based anticancer agents: A comprehensive review

• Published in: Heterocyclic Communications Vol. 31; no. 1; pp. 105076 - 21
• Main Authors: Al-Jumaili Mohammed Hadi Ali, Bakr Ekhlas Aziz, Huessien Mohanad A., Hamed Ahmed Solaiman, Muhaidi Mohammed J.
• Format: Journal Article
• Language: English
• Published: Berlin Walter de Gruyter GmbH 25.02.2025; De Gruyter
• Subjects: Alkylation; anticancer agents; Anticancer properties; biological activity; Cancer therapies; Cell division; Chemotherapy; cytotoxic; Doxorubicin; Drugs; Heterocyclic compounds; mechanisms; medicinal chemistry; Pharmacology; Side effects; Vomiting

This review article summarizes the role of heterocyclic compounds as anticancer drugs used against various human cancers, including doxorubicin, cisplatin, paclitaxel, and resveratrol, which are among the most effective therapeutic agents. Chemotherapy, a treatment modality, exerts its effects on tu...