Coronary Stents: History, Design, and Construction

The history of percutaneous coronary intervention (PCI) is marked by rapid technological advancements that have taken place over the past 40 years. After a period of balloon angioplasty, which was marred by risk of abrupt vessel closure and vessel recoil, balloon expandable metal alloy stents were t...

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Published inJournal of clinical medicine Vol. 7; no. 6; p. 126
Main Authors Schmidt, Torrey, Abbott, J Dawn
Format Journal Article
LanguageEnglish
Published Switzerland MDPI 29.05.2018
MDPI AG
Subjects
drug elution
percutaneous coronary intervention
polymer
Review
stents
polymer
drug elution
percutaneous coronary intervention
stents
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Abstract The history of percutaneous coronary intervention (PCI) is marked by rapid technological advancements that have taken place over the past 40 years. After a period of balloon angioplasty, which was marred by risk of abrupt vessel closure and vessel recoil, balloon expandable metal alloy stents were the mainstay of PCI. The introduction of drug eluting stents (DES) targeted in-stent restenosis, a common mode of stent failure, and ushered in the current PCI era. Since the first generation of DES, advances in polymer science and stent design have advanced the field. The current generation of DES has thin struts, are highly deliverable, have biocompatible or absorbable polymers, and outstanding safety and efficacy profiles. In this review, we discuss the technological advancements in stent development, design, and construction, with an emphasis on balloon expandable stents. The aspects of stent properties, metal alloys, bioresorbable vascular scaffolds, drug elution, and polymers will be covered.
AbstractList The history of percutaneous coronary intervention (PCI) is marked by rapid technological advancements that have taken place over the past 40 years. After a period of balloon angioplasty, which was marred by risk of abrupt vessel closure and vessel recoil, balloon expandable metal alloy stents were the mainstay of PCI. The introduction of drug eluting stents (DES) targeted in-stent restenosis, a common mode of stent failure, and ushered in the current PCI era. Since the first generation of DES, advances in polymer science and stent design have advanced the field. The current generation of DES has thin struts, are highly deliverable, have biocompatible or absorbable polymers, and outstanding safety and efficacy profiles. In this review, we discuss the technological advancements in stent development, design, and construction, with an emphasis on balloon expandable stents. The aspects of stent properties, metal alloys, bioresorbable vascular scaffolds, drug elution, and polymers will be covered.
Author Schmidt, Torrey
Abbott, J Dawn
AuthorAffiliation Department of Medicine, Division of Cardiology, Rhode Island Hospital, Brown Medical School, Providence, RI 02903, USA; torrey.schmidt@lifespan.org
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  givenname: J Dawn
  surname: Abbott
  fullname: Abbott, J Dawn
  email: JAbbott@Lifespan.org
  organization: Department of Medicine, Division of Cardiology, Rhode Island Hospital, Brown Medical School, Providence, RI 02903, USA. JAbbott@Lifespan.org
BackLink https://www.ncbi.nlm.nih.gov/pubmed/29843465$$D View this record in MEDLINE/PubMed
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Keywords polymer
drug elution
percutaneous coronary intervention
stents
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SubjectTerms drug elution
percutaneous coronary intervention
polymer
Review
stents
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Title Coronary Stents: History, Design, and Construction
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