Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions
The interaction of opioids and stimulants is well established; however, the mechanisms that underlie the role that opioid receptors play in psychostimulant action are not. Nociceptin/orphaninFQ (N/OFQ), the endogenous agonist at NOP receptors, attenuates the behavioral effects of cocaine. The effect...
Saved in:
| Published in | Journal of molecular neuroscience Vol. 31; no. 2; pp. 159 - 164 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Springer Nature B.V
01.01.2007
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0895-8696 1559-1166 |
| DOI | 10.1385/JMN/31:02:159 |
Cover
Loading…
| Abstract | The interaction of opioids and stimulants is well established; however, the mechanisms that underlie the role that opioid receptors play in psychostimulant action are not. Nociceptin/orphaninFQ (N/OFQ), the endogenous agonist at NOP receptors, attenuates the behavioral effects of cocaine. The effects of cocaine on N/OFQ were examined in rats using immunoautoradiographic and RIA techniques. Chronic administration of cocaine decreased N/OFQ in medial regions of the caudate putamen, the nucleus accumbens shell, and the substantia nigra. These studies show that N/OFQ levels are altered by treatment with cocaine. Furthermore, the changes in N/OFQ parallel those seen for kappa-opioid receptors, suggesting that the interactions between cocaine and these systems might be similar. |
|---|---|
| AbstractList | The interaction of opioids and stimulants is well established; however, the mechanisms that underlie the role that opioid receptors play in psychostimulant action are not. Nociceptin/orphaninFQ (N/OFQ), the endogenous agonist at NOP receptors, attenuates the behavioral effects of cocaine. The effects of cocaine on N/OFQ were examined in rats using immunoautoradiographic and RIA techniques. Chronic administration of cocaine decreased N/OFQ in medial regions of the caudate putamen, the nucleus accumbens shell, and the substantia nigra. These studies show that N/OFQ levels are altered by treatment with cocaine. Furthermore the changes in N/OFQ parallel those seen for K-opioid receptors, suggesting that the interactions between cocaine and these systems might be similar.[PUBLICATION ABSTRACT] The interaction of opioids and stimulants is well established; however, the mechanisms that underlie the role that opioid receptors play in psychostimulant action are not. Nociceptin/orphaninFQ (N/OFQ), the endogenous agonist at NOP receptors, attenuates the behavioral effects of cocaine. The effects of cocaine on N/OFQ were examined in rats using immunoautoradiographic and RIA techniques. Chronic administration of cocaine decreased N/OFQ in medial regions of the caudate putamen, the nucleus accumbens shell, and the substantia nigra. These studies show that N/OFQ levels are altered by treatment with cocaine. Furthermore, the changes in N/OFQ parallel those seen for kappa-opioid receptors, suggesting that the interactions between cocaine and these systems might be similar.The interaction of opioids and stimulants is well established; however, the mechanisms that underlie the role that opioid receptors play in psychostimulant action are not. Nociceptin/orphaninFQ (N/OFQ), the endogenous agonist at NOP receptors, attenuates the behavioral effects of cocaine. The effects of cocaine on N/OFQ were examined in rats using immunoautoradiographic and RIA techniques. Chronic administration of cocaine decreased N/OFQ in medial regions of the caudate putamen, the nucleus accumbens shell, and the substantia nigra. These studies show that N/OFQ levels are altered by treatment with cocaine. Furthermore, the changes in N/OFQ parallel those seen for kappa-opioid receptors, suggesting that the interactions between cocaine and these systems might be similar. The interaction of opioids and stimulants is well established; however, the mechanisms that underlie the role that opioid receptors play in psychostimulant action are not. Nociceptin/orphaninFQ (N/OFQ), the endogenous agonist at NOP receptors, attenuates the behavioral effects of cocaine. The effects of cocaine on N/OFQ were examined in rats using immunoautoradiographic and RIA techniques. Chronic administration of cocaine decreased N/OFQ in medial regions of the caudate putamen, the nucleus accumbens shell, and the substantia nigra. These studies show that N/OFQ levels are altered by treatment with cocaine. Furthermore the changes in N/OFQ parallel those seen for K-opioid receptors, suggesting that the interactions between cocaine and these systems might be similar. The interaction of opioids and stimulants is well established; however, the mechanisms that underlie the role that opioid receptors play in psychostimulant action are not. Nociceptin/orphaninFQ (N/OFQ), the endogenous agonist at NOP receptors, attenuates the behavioral effects of cocaine. The effects of cocaine on N/OFQ were examined in rats using immunoautoradiographic and RIA techniques. Chronic administration of cocaine decreased N/OFQ in medial regions of the caudate putamen, the nucleus accumbens shell, and the substantia nigra. These studies show that N/OFQ levels are altered by treatment with cocaine. Furthermore, the changes in N/OFQ parallel those seen for kappa-opioid receptors, suggesting that the interactions between cocaine and these systems might be similar. |
| Author | Collins, Stephanie L. Izenwasser, Sari D'Addario, Claudio Romualdi, Patrizia Wade, Dean Candeletti, Sanzio Di Benedetto, Manuela |
| Author_xml | – sequence: 1 givenname: Patrizia surname: Romualdi fullname: Romualdi, Patrizia – sequence: 2 givenname: Manuela surname: Di Benedetto fullname: Di Benedetto, Manuela – sequence: 3 givenname: Claudio surname: D'Addario fullname: D'Addario, Claudio – sequence: 4 givenname: Stephanie L. surname: Collins fullname: Collins, Stephanie L. – sequence: 5 givenname: Dean surname: Wade fullname: Wade, Dean – sequence: 6 givenname: Sanzio surname: Candeletti fullname: Candeletti, Sanzio – sequence: 7 givenname: Sari surname: Izenwasser fullname: Izenwasser, Sari |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/17478889$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkc1P3DAQxS0EgmXhyLWyeuCWrie2Y2dv1YotoAWEBFwtxxm3WWWTrZ1U4r-v-TwgJE4zGv3eaOa9Q7Lb9R0ScgLsB3AtZ5dX1zMOc5bPQZY7ZAJSlhlAUeySCdOlzHRRFgfkMMY1YzkI0PvkAJRQWutyQh4Wf0LfNY663tmmQ7oNfT06jLRGF9DG1DUdvZ7dLG_pFrdDUyNt8R-2z_OILbqBBjvQKiQ9Dfi76bt4RPa8bSMev9YpuV-e3S3Os9XNr4vFz1XmuBJDJl3FS-lRePReg9Sc85LXWCoHIFF6yZRnFpSrhBC50goqXwEIVhfO25xPyenL3nT23xHjYDZNdNi2tsN-jEYxoSCX8kswB86UZjyB3z-A634MXXrCaJ1sBZYunJJvr9BYbbA229BsbHg0b74mgL8ALvQxBvTGNYMdkjVDsqk1wMxTeialZzgYlpuUXlJlH1Tviz_l_wMhb5mp |
| CitedBy_id | crossref_primary_10_1176_appi_ajp_2019_18081007 crossref_primary_10_1016_j_drugalcdep_2016_07_002 crossref_primary_10_1016_j_peptides_2008_09_007 crossref_primary_10_1111_jnc_14209 crossref_primary_10_1016_j_pnpbp_2013_10_016 crossref_primary_10_1002_cne_70003 crossref_primary_10_1007_s00213_016_4385_8 crossref_primary_10_1016_j_neuropharm_2008_05_010 crossref_primary_10_1016_j_phrs_2016_10_023 crossref_primary_10_1089_acu_2009_0669 |
| Cites_doi | 10.1046/j.1471-4159.1999.0730179.x 10.1016/0006-8993(96)00476-3 10.1002/(SICI)1096-9861(19971208)389:1<1::AID-CNE1>3.0.CO;2-6 10.1016/S0091-3057(98)00261-5 10.1523/JNEUROSCI.16-11-03727.1996 10.1002/syn.10091 10.1016/0306-4522(96)00322-3 10.1016/S0166-4328(01)00375-8 10.1016/S0006-8993(00)02669-X 10.1097/00008877-200205000-00006 10.1016/0006-8993(92)90912-S 10.1016/0169-328X(95)00319-N 10.1016/0014-2999(95)00828-4 10.1007/s00213-002-1192-1 10.1016/0169-328X(92)90198-K 10.1016/S0014-2999(01)01194-3 10.1385/JMN:22:3:213 10.1016/0169-328X(96)00091-5 10.1002/syn.890030108 10.1016/S0361-9230(00)00328-2 10.1007/s002130000609 10.1097/00001756-199408150-00018 |
| ContentType | Journal Article |
| Copyright | Humana Press Inc. 2007 |
| Copyright_xml | – notice: Humana Press Inc. 2007 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7QL 7QR 7T7 7TK 7U9 7X7 7XB 88E 88G 8AO 8FD 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR C1K CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ H94 K9. M0S M1P M2M M7N P64 PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS PSYQQ Q9U 7X8 |
| DOI | 10.1385/JMN/31:02:159 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Bacteriology Abstracts (Microbiology B) Chemoreception Abstracts Industrial and Applied Microbiology Abstracts (Microbiology A) Neurosciences Abstracts Virology and AIDS Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) ProQuest Pharma Collection Technology Research Database Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central Environmental Sciences and Pollution Management ProQuest One ProQuest Central Korea Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni) Medical Database Psychology Database Algology Mycology and Protozoology Abstracts (Microbiology C) Biotechnology and BioEngineering Abstracts ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Psychology ProQuest Central Basic MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology ProQuest Central Student Technology Research Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Pharma Collection ProQuest Central China Environmental Sciences and Pollution Management ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) Health & Medical Research Collection AIDS and Cancer Research Abstracts Chemoreception Abstracts Industrial and Applied Microbiology Abstracts (Microbiology A) ProQuest Central (New) ProQuest Medical Library (Alumni) Virology and AIDS Abstracts ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Psychology Journals (Alumni) Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts ProQuest Health & Medical Complete ProQuest Medical Library ProQuest Psychology Journals ProQuest One Academic UKI Edition Engineering Research Database ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | ProQuest One Psychology MEDLINE - Academic Neurosciences Abstracts MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Anatomy & Physiology |
| EISSN | 1559-1166 |
| EndPage | 164 |
| ExternalDocumentID | 2419979401 17478889 10_1385_JMN_31_02_159 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- -Y2 .86 .GJ .VR 06C 06D 0R~ 0VX 0VY 1N0 2.D 203 28- 29L 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2VQ 2~H 30V 3SX 4.4 406 408 40D 40E 44B 53G 5GY 5RE 5VS 67N 6NX 78A 7X7 88E 8AO 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AAPKM AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYTO AAYXX AAYZH ABAKF ABBRH ABDBE ABDZT ABECU ABFSG ABFTV ABHLI ABHQN ABJNI ABJOX ABKCH ABMNI ABMQK ABNWP ABPLI ABQBU ABQSL ABSXP ABTEG ABTHY ABTKH ABTMW ABUWG ABWNU ABXPI ACAOD ACBXY ACCUX ACDTI ACGFS ACHSB ACHXU ACIWK ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACPRK ACSNA ACSTC ACZOJ ADBBV ADHHG ADHIR ADHKG ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADYPR ADZKW AEBTG AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AEZWR AFBBN AFDZB AFEXP AFGCZ AFHIU AFKRA AFLOW AFOHR AFQWF AFRAH AFWTZ AFZKB AGAYW AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGQPQ AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHKAY AHMBA AHPBZ AHSBF AHWEU AIAKS AIGIU AIIXL AILAN AITGF AIXLP AJBLW AJRNO AJZVZ AKMHD ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARMRJ ASPBG ATHPR AVWKF AXYYD AYFIA AZFZN AZQEC B-. BA0 BBWZM BDATZ BENPR BGNMA BPHCQ BSONS BVXVI CAG CCPQU CITATION COF CS3 CSCUP DDRTE DNIVK DPUIP DU5 DWQXO EBD EBLON EBS EIOEI EJD EMOBN ESBYG F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNUQQ GNWQR GQ7 H13 HF~ HG6 HMCUK HMJXF HRMNR HVGLF HZ~ IJ- IKXTQ ITM IWAJR I~X I~Z J-C J0Z JBSCW JZLTJ KOV LLZTM M1P M2M M4Y MA- MVM N2Q N9A NDZJH NF0 NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OVD P19 P2P PF0 PHGZM PHGZT PQQKQ PROAC PSQYO PSYQQ PT4 PT5 Q2X QOK QOR QOS R4E R89 R9I RHV RNI RNS ROL RPX RSV RZK S16 S1Z S26 S27 S28 S3A S3B SAP SBL SBY SCLPG SDH SDM SHX SISQX SJYHP SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZN T13 T16 TEORI TSG TUC TUS U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W48 WK6 WK8 YLTOR ZMTXR ZOVNA ~A9 ~EX -4W -56 -5G -BR -EM -~C 3V. ADINQ CGR CUY CVF ECM EIF GQ6 NPM Z7U Z82 Z83 Z87 Z8O Z8V Z91 7QL 7QR 7T7 7TK 7U9 7XB 8FD 8FK ABRTQ C1K FR3 H94 K9. M7N P64 PJZUB PKEHL PPXIY PQEST PQUKI PRINS Q9U 7X8 |
| ID | FETCH-LOGICAL-c374t-5cb395fe4feff815833393de97c115e5f507f0a17cb44427871bfb1140d6cfa23 |
| IEDL.DBID | 7X7 |
| ISSN | 0895-8696 |
| IngestDate | Tue Aug 05 10:26:49 EDT 2025 Fri Jul 11 09:33:39 EDT 2025 Mon Aug 18 00:02:42 EDT 2025 Wed Feb 19 02:09:36 EST 2025 Tue Jul 01 03:06:33 EDT 2025 Thu Apr 24 23:02:45 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 2 |
| Language | English |
| License | https://www.springer.com/tdm |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c374t-5cb395fe4feff815833393de97c115e5f507f0a17cb44427871bfb1140d6cfa23 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 |
| PMID | 17478889 |
| PQID | 881661039 |
| PQPubID | 326248 |
| PageCount | 6 |
| ParticipantIDs | proquest_miscellaneous_70471255 proquest_miscellaneous_21307803 proquest_journals_881661039 pubmed_primary_17478889 crossref_citationtrail_10_1385_JMN_31_02_159 crossref_primary_10_1385_JMN_31_02_159 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2007-01-01 |
| PublicationDateYYYYMMDD | 2007-01-01 |
| PublicationDate_xml | – month: 01 year: 2007 text: 2007-01-01 day: 01 |
| PublicationDecade | 2000 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Totowa |
| PublicationSubtitle | MN |
| PublicationTitle | Journal of molecular neuroscience |
| PublicationTitleAlternate | J Mol Neurosci |
| PublicationYear | 2007 |
| Publisher | Springer Nature B.V |
| Publisher_xml | – name: Springer Nature B.V |
| References | N. P. Murphy (3102159_CR16) 1996; 75 S. L. Collins (3102159_CR1) 2001; 426 M. Di Benedetto (3102159_CR4) 2004; 22 E. M. Unterwald (3102159_CR24) 1992; 584 S. P. Sivam (3102159_CR22) 1989; 250 P. Kunko (3102159_CR10) 1998; 285 J. Kotlinska (3102159_CR9) 2002; 13 S. Narayanan (3102159_CR17) 1999; 63 N. Laprade (3102159_CR11) 1996; 16 M. E. A. Reith (3102159_CR20) 1987; 243 K. Ploj (3102159_CR19) 2000; 53 Y. L. Hurd (3102159_CR7) 1992; 16 S. L. Collins (3102159_CR2) 2002; 45 R. P. Hammer Jr. (3102159_CR6) 1989; 3 E. M. Unterwald (3102159_CR25) 1994; 5 K. Lutfy (3102159_CR13) 2002; 164 R. Spangler (3102159_CR23) 1996; 38 S. Izenwasser (3102159_CR8) 1996; 297 S. Narayanan (3102159_CR18) 2002; 131 M. J. Mijnster (3102159_CR14) 1997; 389 D. P. Devine (3102159_CR3) 1996; 727 K. Lutfy (3102159_CR12) 2001; 154 P. Romualdi (3102159_CR21) 1996; 40 S. Florin (3102159_CR5) 2000; 880 N. P. Murphy (3102159_CR15) 1999; 73 |
| References_xml | – volume: 73 start-page: 179 year: 1999 ident: 3102159_CR15 publication-title: J. Neurochem. doi: 10.1046/j.1471-4159.1999.0730179.x – volume: 727 start-page: 225 year: 1996 ident: 3102159_CR3 publication-title: Brain Res. doi: 10.1016/0006-8993(96)00476-3 – volume: 389 start-page: 1 year: 1997 ident: 3102159_CR14 publication-title: J. Comp. Neurol. doi: 10.1002/(SICI)1096-9861(19971208)389:1<1::AID-CNE1>3.0.CO;2-6 – volume: 63 start-page: 271 year: 1999 ident: 3102159_CR17 publication-title: Pharmacol. Biochem. Behav. doi: 10.1016/S0091-3057(98)00261-5 – volume: 16 start-page: 3727 year: 1996 ident: 3102159_CR11 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.16-11-03727.1996 – volume: 45 start-page: 153 year: 2002 ident: 3102159_CR2 publication-title: Synapse doi: 10.1002/syn.10091 – volume: 75 start-page: 1 year: 1996 ident: 3102159_CR16 publication-title: Neuroscience doi: 10.1016/0306-4522(96)00322-3 – volume: 131 start-page: 97 year: 2002 ident: 3102159_CR18 publication-title: Behav. Brain Res. doi: 10.1016/S0166-4328(01)00375-8 – volume: 250 start-page: 818 year: 1989 ident: 3102159_CR22 publication-title: J. Pharmacol. Exp. Ther. – volume: 880 start-page: 11 year: 2000 ident: 3102159_CR5 publication-title: Brain Res. doi: 10.1016/S0006-8993(00)02669-X – volume: 13 start-page: 229 year: 2002 ident: 3102159_CR9 publication-title: Behav. Pharmacol. doi: 10.1097/00008877-200205000-00006 – volume: 584 start-page: 314 year: 1992 ident: 3102159_CR24 publication-title: Brain Res. doi: 10.1016/0006-8993(92)90912-S – volume: 38 start-page: 71 year: 1996 ident: 3102159_CR23 publication-title: Brain Res. Mol. Brain Res. doi: 10.1016/0169-328X(95)00319-N – volume: 297 start-page: 187 year: 1996 ident: 3102159_CR8 publication-title: Eur. J. Pharmacol. doi: 10.1016/0014-2999(95)00828-4 – volume: 285 start-page: 277 year: 1998 ident: 3102159_CR10 publication-title: J. Pharmacol. Exp. Ther. – volume: 164 start-page: 168 year: 2002 ident: 3102159_CR13 publication-title: Psychopharmacology doi: 10.1007/s00213-002-1192-1 – volume: 16 start-page: 97 year: 1992 ident: 3102159_CR7 publication-title: Brain Res. Mol. Brain Res. doi: 10.1016/0169-328X(92)90198-K – volume: 243 start-page: 281 year: 1987 ident: 3102159_CR20 publication-title: J. Pharmacol. Exp. Ther. – volume: 426 start-page: 25 year: 2001 ident: 3102159_CR1 publication-title: Eur. J. Pharmacol. doi: 10.1016/S0014-2999(01)01194-3 – volume: 22 start-page: 213 year: 2004 ident: 3102159_CR4 publication-title: J. Mol. Neurosci. doi: 10.1385/JMN:22:3:213 – volume: 40 start-page: 153 year: 1996 ident: 3102159_CR21 publication-title: Brain Res. Mol. Brain Res. doi: 10.1016/0169-328X(96)00091-5 – volume: 3 start-page: 55 year: 1989 ident: 3102159_CR6 publication-title: Synapse doi: 10.1002/syn.890030108 – volume: 53 start-page: 219 year: 2000 ident: 3102159_CR19 publication-title: Brain Res. Bull. doi: 10.1016/S0361-9230(00)00328-2 – volume: 154 start-page: 1 year: 2001 ident: 3102159_CR12 publication-title: Psychopharmacology doi: 10.1007/s002130000609 – volume: 5 start-page: 1613 year: 1994 ident: 3102159_CR25 publication-title: Neuroreport doi: 10.1097/00001756-199408150-00018 |
| SSID | ssj0021418 |
| Score | 1.8392458 |
| Snippet | The interaction of opioids and stimulants is well established; however, the mechanisms that underlie the role that opioid receptors play in psychostimulant... |
| SourceID | proquest pubmed crossref |
| SourceType | Aggregation Database Index Database Enrichment Source |
| StartPage | 159 |
| SubjectTerms | Animals Caudate Nucleus - drug effects Caudate Nucleus - metabolism Central Nervous System Stimulants - administration & dosage Central Nervous System Stimulants - pharmacology Cocaine Cocaine - administration & dosage Cocaine - pharmacology Neurology Nociceptin Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Opioid Peptides - metabolism Putamen - drug effects Putamen - metabolism Radioimmunoassay Rats Rats, Sprague-Dawley Rodents Substantia Nigra - drug effects Substantia Nigra - metabolism |
| Title | Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/17478889 https://www.proquest.com/docview/881661039 https://www.proquest.com/docview/21307803 https://www.proquest.com/docview/70471255 |
| Volume | 31 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3Nb9sgFEdbe9ll2tZ9ZF1bDlNPQwEDNu5lSqZGVaV6H1qn3JDBIFXqnGxOD_vv9x4haS_pyZZBMuIB75Pfj5CPwrSuBseCFbWTTMXCMxNCyWSIgWseQOvjBeerpry4VpdzPc-1OUMuq9yciemg7hYeY-RjgwkuzFt-Xv5hSBqFydXMoPGU7CNyGVZ0VfN7f0uoFN7jptbMlHWZITal0ePLq2YsxRkvzgSilD5USTvszKRvZi_I82wo0slasi_Jk9C_IgeTHpzk3__oKU2lmykmfkB-ZYhbCqcbePqBLhOOaxhol6zCAd5uetqMv86-0yXWsXSB3mK5UPo-JC4cCmuBOmSMoMjWAKvxNbmenf_8csEyYQLzslIrpr2TtY5BxRCjEXihStayC3XlwfALOoLxF3krKu-UQo6NSrjowCPiXeljW8g3ZK9f9OEdoZ1HIBdhQhStMqFyznHPnQIDBTwSrUfk02bOrM9o4khqcWtTisxoC1NspbC8sDDFI3K67b5cw2js6ni4EYDNu2mwW9mPyMm2FbYB5jbaPizuBluALq4Ml7t7VBz0cBr527Vc7weSOARM_f7Rfx-SZ-u4LoZfPpC91d-7cAQGycodp2V3TPYns-m0gef0vPn24z_WP-Cj |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwELaq7QEuCCiPpUB9gJ6I1o7txKmEUIGuto9dHmpRbyZ2bAmpzW7JVqg_iv_IjJMsXJZbb1FiKZY9nvnm4fkIecV1aQtwLJK0sCKRIXWJ9j5LhA-eKebB6uMF5-ksm5zJo3N1vkF-93dhsKyy14lRUVdzhzHykcYEF-Yt3y2uEiSNwuRqz6DRSsWxv_kFHlvz9vAjbO_rNB0fnH6YJB2pQOJELpeJclYUKngZfAia46UjUYjKF7kDcORVAIAUWMlzZ6VEHoqc22DBa2BV5kKJfQ5A429KAZ7MgGy-P5h9_rry8LiMAUWmC5XorMi6pp5Cq9HRdDYSfI-lexz7ov5rBNcg22jhxvfJvQ6a0v1Wlh6QDV8_JFv7Nbjllzd0l8Zi0RiF3yLfuqa6FPRpCUCVLmLnWN_QKuLQBp5-1HQ2-jT-QhdYOVN5eoEFSvF9E9l3KEgftchRQZEfAuT_ETm7ldV8TAb1vPZPCa0cto7h2gdeSu1zay1zzEqAROADKTUkb_o1M67rX440GhcmJuW0MrDERnDDUgNLPCS7q-GLtnHHuoHb_QaY7vw2ZiVtQ7Kz-goHD7MpZe3n141Jwfrnmon1I3IGlj_O_Em7r38nElkLdPHsv__eIXcmp9MTc3I4O94md9uoMgZ_npPB8ue1fwFwaGlfdkJIyffblvs_L4Ebrw |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwELaqVkJcEFAeS4H6AD0RxY7txKlUoYqy6oMuIFG0NxM7toRUsttmq6o_rf-OGSfZclluvUWJpVj2zPibh-cj5B3XlS3BsUiy0opEhswl2vs8ET54ppiHUx8vOJ9O8sMzeTxV0zVyO9yFwbLKwSZGQ13PHMbIU40JLsxbpqGvivh2MP44v0iQQAoTrQObRichJ_7mGry3du_oALb6fZaNP__4dJj0BAOJE4VcJMpZUargZfAhaI4XkEQpal8WDoCSVwHAUmAVL5yVEjkpCm6DBQ-C1bkLFfY8AOu_UQjFUcWK6Z2vx2UMLTJdqkTnZd639xRapcenk1TwXZbtcuyQ-u9xuALjxrNu_Jg86kEq3e-k6glZ881TsrnfgIP-54bu0Fg2GuPxm-Rn316XgmWtALLSeewh61taR0TawtPvhk7Sr-PvdI41NLWn51iqFN-3kYeHghxSi2wVFJkiQBOekbN7WcvnZL2ZNf4lobXDJjJc-8ArqX1hrWWOWQngCLwhpUbkw7BmxvWdzJFQ49zE9JxWBpbYCG5YZmCJR2RnOXzetfBYNXBr2ADTa3JrlnI3ItvLr6CCmFepGj-7ak0GOKDQTKweUTDAAHHmL7p9vZtI5C_Q5av__nubPABpN1-OJidb5GEXXsYo0Guyvri88m8AFy3s2yiBlPy6b5H_C2coHn8 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Chronic+cocaine+produces+decreases+in+N%2FOFQ+peptide+levels+in+select+rat+brain+regions&rft.jtitle=Journal+of+molecular+neuroscience&rft.au=Romualdi%2C+Patrizia&rft.au=Di+Benedetto%2C+Manuela&rft.au=D%27Addario%2C+Claudio&rft.au=Collins%2C+Stephanie+L&rft.date=2007-01-01&rft.issn=0895-8696&rft.volume=31&rft.issue=2&rft.spage=159&rft_id=info:doi/10.1385%2FJMN%2F31%3A02%3A159&rft_id=info%3Apmid%2F17478889&rft.externalDocID=17478889 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0895-8696&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0895-8696&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0895-8696&client=summon |