Allylic cross-coupling using aromatic aldehydes as α-alkoxyalkyl anions

• Published in: Beilstein journal of organic chemistry Vol. 16; no. 1; pp. 185 - 189
• Main Authors: Yuasa, Akihiro, Nagao, Kazunori, Ohmiya, Hirohisa
• Format: Journal Article
• Language: English
• Published: Germany Beilstein-Institut 07.02.2020
• Subjects: aldehyde; Chemistry; copper; copper catalysis; cross-coupling; Letter; palladium; synthetic method; cross-coupling; copper catalysis; aldehyde; copper; palladium; synthetic method

The allylic cross-coupling using aromatic aldehydes as α-alkoxyalkyl anions is described. The synergistic palladium/copper-catalyzed reaction of aromatic aldehydes, allylic carbonates, and a silylboronate produces the corresponding homoallylic alcohol derivatives. This process involves the catalytic...