Effect of reserpine in Raynaud's phenomenon

• Published in: Circulation (New York, N.Y.) Vol. 39; no. 2; pp. 259 - 266
• Main Authors: Kontos, H A, Wasserman, A J
• Format: Journal Article
• Language: English
• Published: United States 01.02.1969
• Subjects: Adult; Blood Pressure - drug effects; Blood Vessels - drug effects; Blood Vessels - physiopathology; Epinephrine - blood; Female; Follow-Up Studies; Hand - blood supply; Humans; Ice; Injections, Intra-Arterial; Male; Middle Aged; Norepinephrine - blood; Raynaud Disease - blood; Raynaud Disease - drug therapy; Raynaud Disease - physiopathology; Reserpine - administration & dosage; Reserpine - pharmacology; Reserpine - therapeutic use; Skin - blood supply; Tyramine - pharmacology; Vascular Resistance - drug effects

The responses of the blood vessels of the hand to intra-arterial infusion of tyramine and to application of ice to the forehead were examined in patients with Raynaud's phenomenon and in normal subjects. The vasoconstrictor responses to tyramine and to ice were not significantly different in th...