Endometrial cell-derived conditioned medium in combination with platelet-rich plasma promotes the development of mouse ovarian follicles

• Published in: Zygote (Cambridge) Vol. 31; no. 1; pp. 1 - 7
• Main Authors: Taghizabet, Neda, Rezaei-Tazangi, Fatemeh, Mousavi, Mahboubeh, Dehghani, Farzaneh, Zareifard, Nehleh, Shabani, Soha, Bahmanpour, Soghra, Aliakbari, Fereshteh, Sadeghzadeh, Zahra, Dortaj, Hengameh, Chakerzehi, Arezoo, Mohseni, Gholamreza
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.02.2023
• Subjects: Animals; Autoimmune diseases; Blood platelets; Cell differentiation; Cell growth; Cell lines; Culture Media, Conditioned - pharmacology; Cyclophosphamide; Endometrium; Female; Fertility; Follicles; Gene expression; Growth differentiation factor 9; Growth factors; Immunohistochemistry; Infertility; Menstruation; Mice; Ovarian Follicle; Ovaries; Platelet-Rich Plasma; Platelets; Polymerase chain reaction; Reproductive technologies; Reverse transcription; Signal transduction; Smad2 protein; Stromal cells; Uterus; Germany

Fertility preservation is one of the most important issues in assisted reproductive technology. Previous studies have shown that cytokines and growth factors can improve follicle growth. The endometrial stromal cells secrete various factors that are involved in maintaining the integrity of uterine a...