Squalamine lactate for the treatment of age-related macular degeneration

• Published in: Expert review of ophthalmology Vol. 2; no. 2; pp. 165 - 175
• Main Authors: Ciulla, Thomas, Oliver, Alexander, Gast, Michael J
• Format: Journal Article
• Language: English
• Published: London Informa Healthcare 01.04.2007; Taylor & Francis
• Subjects: age-related macular degeneration; AMD; antiangiogenesis; Evizon; squalamine; VEGF

Squalamine lactate (Evizon™, Genaera, PA, USA) is a systemically administered antiangiogenic compound that is among the group of drugs being investigated for the treatment of neovascular age-related macular degeneration (AMD). Squalamine lactate is the first drug candidate from the aminosterol class...