Comparative Effectiveness of the Homeopathic Preparation Traumeel S in Third Molar Extraction Surgery: A Preliminary Triple-Blind Clinical Trial

• Published in: Homeopathy : the journal of the Faculty of Homeopathy Vol. 110; no. 4; pp. 229 - 235
• Main Authors: Souza, Glaciele Maria de, Fernandes, Ighor Andrade, Pinheiro, Marcos Luciano Pimenta, Falci, Saulo Gabriel Moreira
• Format: Journal Article
• Language: English
• Published: Rüdigerstraße 14, 70469 Stuttgart, Germany Georg Thieme Verlag KG 01.11.2021
• Subjects: Adult; Anti-Inflammatory Agents - therapeutic use; Dexamethasone - therapeutic use; Double-Blind Method; Edema - drug therapy; Female; Homeopathy; Humans; Male; Minerals; Molar, Third - surgery; Original Research Article; Pain, Postoperative - drug therapy; Plant Extracts; Prospective Studies; Tooth, Impacted - surgery; Young Adult; dexamethasone; oral surgery; homeopathy; third molar
• ISSN: 1475-4916; 1476-4245
• DOI: 10.1055/s-0041-1725038

Abstract Background and Aim  This preliminary study aimed to evaluate whether a homeopathic preparation ( Traumeel S ) might be a good option to control post-operative outcomes (pain, edema and trismus) associated with surgical removal of mandibular third molar teeth. The null hypothesis was that Traumeel S is not different from dexamethasone (gold standard) in controlling these post-operative inflammatory complications. Methods  A randomized, “split-mouth”, triple-blind clinical trial was conducted. Seventeen healthy patients with a mean age of 20.94 ( ± 5.83) years had their lower asymptomatic bilateral third molars removed. Patients were randomized to receive Traumeel S or dexamethasone pre-operatively by injection into the masseter muscle; each patient acted as his/her own control. At 24, 48, 72 hours and 7 days after the surgery, the pain was evaluated according to a visual analog scale, edema through linear measurements of the face, and trismus through the maximum buccal opening. Wilcoxon statistics or paired t -test were used, and a significance level of 95% was adopted. Results  For pain, the results for Traumeel S were not different ( p  > 0.05) from those of dexamethasone after 24 hours, 72 hours, and 7 days. For edema, the results for Traumeel S were not different ( p  > 0.05) from those of dexamethasone at all post-operative evaluations. For mouth opening, the results for Traumeel S were not different ( p  > 0.05) from those of dexamethasone at 72 hours and 7 days after third molar extraction. Conclusion  With the exception of some early post-operative findings, the null hypothesis is not rejected. Traumeel S might be a good alternative approach to dexamethasone for controlling pain, edema and trismus after third molar removal.