Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity

• Published in: Annals of clinical biochemistry Vol. 45; no. Pt 4; p. 364
• Main Authors: Hosogaya, Shigemi, Yatomi, Yutaka, Nakamura, Kazuhiro, Ohkawa, Ryunosuke, Okubo, Shigeo, Yokota, Hiromitsu, Ohta, Masato, Yamazaki, Hirokazu, Koike, Toru, Ozaki, Yukio
• Format: Journal Article
• Language: English
• Published: England 01.07.2008
• Subjects: Female; Health; Humans; Linear Models; Lysophospholipids - blood; Male; Phosphoric Diester Hydrolases - metabolism; Reference Standards

Lysophosphatidic acid (LPA) plays important roles in a variety of biological responses, especially in the area of vascular biology, and the determination of its plasma concentration is believed to be important. Several mechanisms are known to be involved in the metabolism of LPA. To identify factors...