Apolipoprotein M in lipid metabolism and cardiometabolic diseases

• Published in: Current opinion in lipidology Vol. 26; no. 1; p. 48
• Main Authors: Borup, Anna, Christensen, Pernille M, Nielsen, Lars B, Christoffersen, Christina
• Format: Journal Article
• Language: English
• Published: England 01.02.2015
• Subjects: Animals; Apolipoproteins - metabolism; Apolipoproteins M; Cardiovascular Diseases - metabolism; Cardiovascular Diseases - pathology; Endothelial Cells - pathology; Humans; Lipid Metabolism; Lipocalins - metabolism; Lysophospholipids - metabolism; Metabolic Diseases - metabolism; Metabolic Diseases - pathology; Sphingosine - analogs & derivatives; Sphingosine - metabolism

This review will address recent findings on apolipoprotein M (apoM) and its ligand sphingosine-1-phosphate (S1P) in lipid metabolism and inflammatory diseases. ApoM's likely role(s) in health and disease has become more diverse after the discovery that apoM functions as a chaperone for S1P. Hen...