A red-fleshed apple rich in anthocyanins improves endothelial function, reduces inflammation, and modulates the immune system in hypercholesterolemic subjects: the AppleCOR study - Pedret, Anna; Companys, Judit; Calderón-Pérez, Lorena; Llauradó, Elisabet; Pla-Pagà, Laura; Salamanca, Patricia; Sandoval-Ramírez, Berner-Andree; Catalán, Úrsula; Fernández-Castillejo, Sara; Yuste, Silvia; Macià, Alba; Gutiérrez-Tordera, Laia; et al. (Food & function, 2024)
Keywords: Acute effects; Adult; Aged; Anthocyanins; Anthocyanins - administration & dosage; Anthocyanins - pharmacology; Apples; Biomarkers; C-Reactive Protein; Complement system; Consumption; Female; Fruit - chemistry; Fruits; Health risks; Humans; Hypercholesterolemia - drug therapy; Hyperemia; Immune system; Immune System - drug effects; Immunoglobulins; Inflammation; Ischemia; Lipids; Male; Malus - chemistry; Middle Aged; P-selectin; Photinia - chemistry; Plant Extracts - pharmacology; Proteins; Proteomics