Appraisal of antioxidant potential and biological studies of bogan bail (Bougainvillea glabra) leaf extracts using different solvents

Current research work was performed to evaluate the antioxidant, antidiabetic, thrombolytic, and cytotoxic potential of Bougainvillea glabra leaf extracts with different solvents. Extraction of leaves was carried out by maceration using solvents of various polarity such as n-hexane, chloroform, ethy...

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Published inCzech Journal of Food Sciences Vol. 39; no. 3; pp. 176 - 180
Main Authors Riaz, Muhammad, Fatima, Humaira, Misbah ur Rehman, Muhammad, Qadir, Rahman, Hussain, Shabbir, Hafeez, Abdul, Siddique, Abu Bakar
Format Journal Article
LanguageEnglish
Published Prague Czech Academy of Agricultural Sciences (CAAS) 01.01.2021
Czech Academy of Agricultural Sciences
Subjects
Acetic acid
antidiabetic
Antioxidants
b. glabra
Bougainvillea glabra
Butanol
Chloroform
Cytotoxicity
Diabetes mellitus
Erythrocytes
Ethyl acetate
Evaluation
Flavonoids
Free radicals
hemolytic
Hexanes
Leaves
Lysis
n-Hexane
Pharmaceutical industry
Phenolic compounds
Phenols
Plant extracts
Polarity
Scavenging
Solvents
Thrombolysis
thrombolytic
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Summary:Current research work was performed to evaluate the antioxidant, antidiabetic, thrombolytic, and cytotoxic potential of Bougainvillea glabra leaf extracts with different solvents. Extraction of leaves was carried out by maceration using solvents of various polarity such as n-hexane, chloroform, ethyl acetate, n-butanol, and methanol. The highest values of total phenolic and flavonoid contents were assessed in methanolic extract, such as 58.57% and 29.41%, respectively. Antioxidant potential was measured by DPPH free radical, showing 65.16% scavenging activity in methanolic extract. Similarly, the reducing power of methanolic extract was also measured. Hemolytic activity of B. glabra leaf extracts was evaluated, and maximum percentage lysis was found as 6.86% in chloroform extract. The thrombolytic activity of B. glabra leaf extracts was evaluated against human red blood cells, and the maximum percentage of clot lysis was 59.10% in chloroform extract. Maximum antidiabetic activity (16.20%) was observed in methanolic extract. Overall, the presented results reveal that bogan bail extract is capable of being employed in nutra-pharmaceutical industry.
ISSN:1212-1800
1805-9317
DOI:10.17221/273/2020-CJFS