Influence of secular trends and sample size on reference equations for lung function tests

• Published in: The European respiratory journal Vol. 37; no. 3; pp. 658 - 664
• Main Authors: Quanjer, P.H., Stocks, J., Cole, T.J., Hall, G.L., Stanojevic, S.
• Format: Journal Article
• Language: English
• Published: Leeds Maney 01.03.2011
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Child; Child, Preschool; Female; Forced Expiratory Volume; Humans; Infant; Male; Medical sciences; Middle Aged; Pneumology; Reference Values; Respiratory Function Tests - methods; Respiratory Function Tests - standards; Sample Size; Spirometry - methods; Spirometry - standards; Vital Capacity; Spirometry; Multicentre study; Lung function; Sample; Size; secular trends; pulmonary function; Exploration; Equation; reference equations; Pneumology
• ISSN: 0903-1936; 1399-3003; 1399-3003
• DOI: 10.1183/09031936.00110010

The aim of our study was to determine the contribution of secular trends and sample size to lung function reference equations, and establish the number of local subjects required to validate published reference values. 30 spirometry datasets collected between 1978 and 2009 provided data on healthy,...