UHRF1 depletion causes a G2/M arrest, activation of DNA damage response and apoptosis - Tien, Amy L; Senbanerjee, Sucharita; Kulkarni, Atul; Mudbhary, Raksha; Goudreau, Bernadette; Ganesan, Shridar; Sadler, Kirsten C; Ukomadu, Chinweike (Biochemical journal, 2011)
Keywords: Apoptosis; Caspase 3 - metabolism; Caspase 8 - genetics; Caspase 8 - metabolism; CCAAT-Enhancer-Binding Proteins - genetics; CCAAT-Enhancer-Binding Proteins - metabolism; CDC2 Protein Kinase - metabolism; cdc25 Phosphatases - metabolism; Cell Line, Tumor; Checkpoint Kinase 2; DNA Damage - radiation effects; G2 Phase; Gene Silencing; Histones - metabolism; Humans; In Situ Nick-End Labeling; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases - metabolism; Protein Transport; RNA, Messenger - metabolism; RNA, Small Interfering; Ubiquitin-Protein Ligases; Ultraviolet Rays - adverse effects