Involvement of cytotoxic Eomes-expressing CD4⁺ T cells in secondary progressive multiple sclerosis - Raveney, Ben J. E.; Sato, Wakiro; Takewaki, Daiki; Zhang, Chenyang; Kanazawa, Tomomi; Lin, Youwei; Okamoto, Tomoko; Araki, Manabu; Kimura, Yukio; Sato, Noriko; Sano, Terunori; Saito, Yuko; et al. (Proceedings of the National Academy of Sciences - PNAS, 2021)
Keywords: Autoimmune diseases; Autopsies; Autopsy; Biological Sciences; Biomarkers; CD4 antigen; Central nervous system; Cytotoxicity; Granzyme B; Health risks; Helper cells; Inflammation; Lymphocytes; Lymphocytes T; Multiple sclerosis; Neurological diseases; Pathogenesis; Peripheral blood; Risk assessment; Signs and symptoms; Therapeutic targets; autoimmunity; secondary progressive multiple sclerosis; Eomes+ Th cells; biomarkers; multiple sclerosis