Neurofunctional mapping of reward anticipation and outcome for major depressive disorder: a voxel-based meta-analysis

• Published in: Psychological medicine Vol. 52; no. 15; pp. 3309 - 3322
• Main Authors: Yang, Xun, Su, Yueyue, Yang, Fan, Song, Yuan, Yan, Jiangnan, Luo, Ya, Zeng, Jianguang
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.11.2022
• Subjects: Amygdala; Brain mapping; Caudate nucleus; Cerebellum; Cortex; Cortex (cingulate); Cortex (frontal); Depressive personality disorders; Expectations; Frontal gyrus; Magnetic resonance imaging; Mapping; Mental depression; Mental disorders; Mesolimbic system; Meta-analysis; Monetary incentives; Motivation; Neostriatum; Neurobiology; Neuroimaging; Paradigms; Postcentral gyrus; Precentral gyrus; Prefrontal cortex; Reinforcement; Rewards; Temporal gyrus; Temporal lobe; Thalamus; reward; meta-analysis; fMRI; Anticipation; major depressive disorder; outcome

Aberrations in how people form expectations about rewards and how they respond to receiving rewards are thought to underlie major depressive disorder (MDD). However, the underlying mechanism linking the appetitive reward system, specifically anticipation and outcome, is still not fully understood. T...