Effect of Irradiation and Appendicostomy on Appendix Structure and Responses of Appendix Cells to Mitogens

• Published in: The Journal of immunology (1950) Vol. 111; no. 1; pp. 171 - 182
• Main Authors: Blythman, Hildur E, Waksman, Byron H
• Format: Journal Article
• Language: English
• Published: United States Am Assoc Immnol 01.07.1973
• Subjects: Animals; Appendix - cytology; Appendix - drug effects; Appendix - radiation effects; Appendix - surgery; Cells, Cultured; Concanavalin A; DNA - biosynthesis; Dose-Response Relationship, Drug; Endotoxins; Lectins; Lymph Nodes - cytology; Lymph Nodes - radiation effects; Lymphocytes - radiation effects; Lymphoid Tissue - cytology; Macrophages - radiation effects; Mitogens - pharmacology; Mitosis - radiation effects; Peyer's Patches; Rabbits; Radiation Effects; Spleen - cytology; Spleen - radiation effects; Thymus Gland - cytology; Time Factors

Abstract A quantitative morphologic analysis was made of changes in the appendix nodule in rabbits receiving sublethal whole body irradiation and in others after ligation of the base of the appendix, appendicostomy and sterilization of the appendix lumen. After 450 r, the dome, the thymus-dependent...