Identification, in silico screening, and molecular docking of novel ACE inhibitory peptides isolated from the edible symbiot Boletus griseus-Hypomyces chrysospermus

• Published in: Food science & technology Vol. 169; p. 114008
• Main Authors: Renjuan, Li, Xiuli, Zhou, Liping, Sun, Yongliang, Zhuang
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.11.2022
• Subjects: absorption; ACE inhibitory Peptide; active sites; Boletus; computer simulation; computer software; enzymes; excretion; hydrogen; hydrophobicity; In silico screening; metabolism; methanol; Molecular docking; peptides; tandem mass spectrometry; ultra-performance liquid chromatography; In silico screening; ACE inhibitory Peptide; Molecular docking

The aim of this study is to find angiotensin-Ⅰ-converting enzyme inhibitory (ACEI) peptides from the edible symbiot Boletus griseus-Hypomyces chrysospermus (BGHC). The peptides from the methanol extract of BGHC were identified through ultraperformance liquid chromatography quadrupole Orbitrap tandem...