Ultra‐Small Nano‐Assemblies as Tumor‐Targeted and Renal Clearable Theranostic Agent for Photodynamic Therapy

• Published in: Advanced materials (Weinheim) Vol. 35; no. 19; pp. e2209789 - n/a
• Main Authors: Zhang, Dongsheng, Teng, Kun‐Xu, Zhao, Luyang, Niu, Li‐Ya, Yang, Qing‐Zheng
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.05.2023
• Subjects: Animals; Cell Line, Tumor; Clearances; Materials science; Mice; Nanoparticles; Neoplasms - therapy; Photochemotherapy; Photodynamic therapy; Photosensitizing Agents - pharmacology; Photosensitizing Agents - therapeutic use; Precision Medicine; renal clearable; Self-assembly; Side effects; Theranostic Nanomedicine; Triethylene glycol; tumor targeting; Tumors; self-assembly; tumor targeting; renal clearable; photodynamic therapy

It is a challenge to design photosensitizers to balance between the tumor‐targeting enrichment for precise treatment and efficient clearance within a reasonable timescale for reducing side effects. Herein, an ultra‐small nano‐photosensitizer 1a with excellent tumor‐specific accumulation and renal cl...