Microporogen‐Structured Collagen Matrices for Embedded Bioprinting of Tumor Models for Immuno‐Oncology

• Published in: Advanced materials (Weinheim) Vol. 35; no. 33; pp. e2210748 - n/a
• Main Authors: Reynolds, Daniel S., Lázaro, Irene, Blache, Manon L., Liu, Yutong, Jeffreys, Nicholas C., Doolittle, Ramsey M., Grandidier, Estée, Olszewski, Jason, Dacus, Mason T., Mooney, David J., Lewis, Jennifer A.
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 17.08.2023
• Subjects: Antigens; cancer; Cell death; Chitosan; Collagen; embedded bioprinting; Gelatin; immunotherapy; Lymphocytes; Materials science; Microparticles; microporogens; Prepolymers; Rheological properties; Rheology; Three dimensional models; Three dimensional printing; Tissue engineering; Tumors; collagen; cancer; embedded bioprinting; immunotherapy; microporogens

Embedded bioprinting enables the rapid design and fabrication of complex tissues that recapitulate in vivo microenvironments. However, few biological matrices enable good print fidelity, while simultaneously facilitate cell viability, proliferation, and migration. Here, a new microporogen‐structured...