On the Mechanisms of Hypohalous Acid Formation and Electrophilic Halogenation by Non‐Native Halogenases - Prakinee, Kridsadakorn; Lawan, Narin; Phintha, Aisaraphon; Visitsatthawong, Surawit; Chitnumsub, Penchit; Jitkaroon, Watcharapa; Chaiyen, Pimchai (Angewandte Chemie International Edition, 2024)
Keywords: De novo function; Electrophilic halogenation; Enzyme catalysis; Enzymes; Flavin; Flavin reductase; Flavin-dependent enzymes; Flavins - chemistry; Flavins - metabolism; Fluorimetry; Fluorometry; Halides; Halogenation; Hydrogen peroxide; Hydrogen Peroxide - chemistry; Hydrogen Peroxide - metabolism; Hydrolases - chemistry; Hydrolases - metabolism; Kinetics; Mixed Function Oxygenases - chemistry; Mixed Function Oxygenases - metabolism; Mutagenesis; Organic compounds; Oxidoreductases - chemistry; Oxidoreductases - metabolism; Reaction mechanisms; Reductases; Spectrophotometry; Structural analysis; Substrates; Flavin-dependent enzymes; De novo function; Enzyme catalysis; Reaction mechanisms; Electrophilic halogenation