Curcumae Radix: A Review of Traditional Use, Phytochemistry, Pharmacology, Toxicology and Quality Control

Curcumae Radix (CuR) is a traditional Chinese medicine that has been used in China for more than 1,000 years. It has the traditional efficacy of activating blood and relieving pain, promoting qi and relieving depression, clearing heart and cooling blood, and promoting gallbladder and removing jaundi...

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Published inChemistry & biodiversity Vol. 21; no. 5; pp. e202400098 - n/a
Main Authors Niu, Yu‐Ting, Xu, Hao‐Nan, Zhang, Yu‐Ying, Li, Xin‐Zhuo, Li, Yu‐Ze, Song, Xiao‐Mei, Zhang, Dong‐Dong, Wang, Wei
Format Journal Article
LanguageEnglish
Published Switzerland Wiley Subscription Services, Inc 01.05.2024
Subjects
Analgesics
Animals
Antidepressants
Blood
Chemical composition
Chemical compounds
Composition effects
Control systems
Curcuma - chemistry
Curcumae Radix
Diabetes mellitus
Drugs, Chinese Herbal - chemistry
Drugs, Chinese Herbal - isolation & purification
Drugs, Chinese Herbal - pharmacology
Gallbladder
Hepatitis
Herbal medicine
Humans
Hyperplasia
Inflammation
Jaundice
Medicine, Chinese Traditional
Pharmaceuticals
Pharmacology
pharmacology and toxicology
Phytochemicals - chemistry
Phytochemicals - isolation & purification
Phytochemicals - pharmacology
phytochemistry
Quality Control
Terpenes
Toxicity
Toxicology
Traditional Chinese medicine
traditional use
Curcumae Radix
quality control
pharmacology and toxicology
traditional use
phytochemistry
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Abstract Curcumae Radix (CuR) is a traditional Chinese medicine that has been used in China for more than 1,000 years. It has the traditional efficacy of activating blood and relieving pain, promoting qi and relieving depression, clearing heart and cooling blood, and promoting gallbladder and removing jaundice. Based on this, many domestic and foreign scholars have conducted systematic studies on its chemical composition, pharmacological effects, toxicity and quality control. Currently, 250 compounds, mainly including terpenoids and curcuminoids, have been isolated and identified from CuR, which has pharmacological activities, including antitumor, anti‐inflammatory and analgesic, antidepressant, hepatoprotective, hemostatic, hematopoietic, and treatment of diabetes mellitus. In modern clinical practice, CuR is widely used in the treatment of tumors, breast hyperplasia, hepatitis, and stroke. However, the generation of toxicity and clinical application of CuR and Caryophylli Flos, the determination of the concoction process of artifacts, the determination of specific Quality Marker, and the establishment of the quality control system of CuR, are problems that need to be solved urgently at present.
AbstractList Curcumae Radix (CuR) is a traditional Chinese medicine that has been used in China for more than 1,000 years. It has the traditional efficacy of activating blood and relieving pain, promoting qi and relieving depression, clearing heart and cooling blood, and promoting gallbladder and removing jaundice. Based on this, many domestic and foreign scholars have conducted systematic studies on its chemical composition, pharmacological effects, toxicity and quality control. Currently, 250 compounds, mainly including terpenoids and curcuminoids, have been isolated and identified from CuR, which has pharmacological activities, including antitumor, anti-inflammatory and analgesic, antidepressant, hepatoprotective, hemostatic, hematopoietic, and treatment of diabetes mellitus. In modern clinical practice, CuR is widely used in the treatment of tumors, breast hyperplasia, hepatitis, and stroke. However, the generation of toxicity and clinical application of CuR and Caryophylli Flos, the determination of the concoction process of artifacts, the determination of specific Quality Marker, and the establishment of the quality control system of CuR, are problems that need to be solved urgently at present.Curcumae Radix (CuR) is a traditional Chinese medicine that has been used in China for more than 1,000 years. It has the traditional efficacy of activating blood and relieving pain, promoting qi and relieving depression, clearing heart and cooling blood, and promoting gallbladder and removing jaundice. Based on this, many domestic and foreign scholars have conducted systematic studies on its chemical composition, pharmacological effects, toxicity and quality control. Currently, 250 compounds, mainly including terpenoids and curcuminoids, have been isolated and identified from CuR, which has pharmacological activities, including antitumor, anti-inflammatory and analgesic, antidepressant, hepatoprotective, hemostatic, hematopoietic, and treatment of diabetes mellitus. In modern clinical practice, CuR is widely used in the treatment of tumors, breast hyperplasia, hepatitis, and stroke. However, the generation of toxicity and clinical application of CuR and Caryophylli Flos, the determination of the concoction process of artifacts, the determination of specific Quality Marker, and the establishment of the quality control system of CuR, are problems that need to be solved urgently at present.
Curcumae Radix (CuR) is a traditional Chinese medicine that has been used in China for more than 1,000 years. It has the traditional efficacy of activating blood and relieving pain, promoting qi and relieving depression, clearing heart and cooling blood, and promoting gallbladder and removing jaundice. Based on this, many domestic and foreign scholars have conducted systematic studies on its chemical composition, pharmacological effects, toxicity and quality control. Currently, 250 compounds, mainly including terpenoids and curcuminoids, have been isolated and identified from CuR, which has pharmacological activities, including antitumor, anti‐inflammatory and analgesic, antidepressant, hepatoprotective, hemostatic, hematopoietic, and treatment of diabetes mellitus. In modern clinical practice, CuR is widely used in the treatment of tumors, breast hyperplasia, hepatitis, and stroke. However, the generation of toxicity and clinical application of CuR and Caryophylli Flos, the determination of the concoction process of artifacts, the determination of specific Quality Marker, and the establishment of the quality control system of CuR, are problems that need to be solved urgently at present.
Author Li, Xin‐Zhuo
Li, Yu‐Ze
Song, Xiao‐Mei
Wang, Wei
Niu, Yu‐Ting
Zhang, Yu‐Ying
Zhang, Dong‐Dong
Xu, Hao‐Nan
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  surname: Wang
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Keywords Curcumae Radix
quality control
pharmacology and toxicology
traditional use
phytochemistry
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Snippet Curcumae Radix (CuR) is a traditional Chinese medicine that has been used in China for more than 1,000 years. It has the traditional efficacy of activating...
Curcumae Radix (CuR) is a traditional Chinese medicine that has been used in China for more than 1,000 years. It has the traditional efficacy of activating...
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StartPage e202400098
SubjectTerms Analgesics
Animals
Antidepressants
Blood
Chemical composition
Chemical compounds
Composition effects
Control systems
Curcuma - chemistry
Curcumae Radix
Diabetes mellitus
Drugs, Chinese Herbal - chemistry
Drugs, Chinese Herbal - isolation & purification
Drugs, Chinese Herbal - pharmacology
Gallbladder
Hepatitis
Herbal medicine
Humans
Hyperplasia
Inflammation
Jaundice
Medicine, Chinese Traditional
Pharmaceuticals
Pharmacology
pharmacology and toxicology
Phytochemicals - chemistry
Phytochemicals - isolation & purification
Phytochemicals - pharmacology
phytochemistry
Quality Control
Terpenes
Toxicity
Toxicology
Traditional Chinese medicine
traditional use
Title Curcumae Radix: A Review of Traditional Use, Phytochemistry, Pharmacology, Toxicology and Quality Control
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fcbdv.202400098
https://www.ncbi.nlm.nih.gov/pubmed/38462532
https://www.proquest.com/docview/3054953547
https://www.proquest.com/docview/2955268407
Volume 21
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