Engineering of Surface Energy of Cell‐Culture Platform to Enhance the Growth and Differentiation of Dendritic Cells via Vapor‐Phase Synthesized Functional Polymer Films

• Published in: Small (Weinheim an der Bergstrasse, Germany) Vol. 18; no. 17; pp. e2106648 - n/a
• Main Authors: Lee, Minseok, Chun, Dongmin, Park, Seonghyeon, Choi, Goro, Kim, Yesol, Kang, Suk‐Jo, Im, Sung Gap
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.04.2022
• Subjects: Antigen Presentation; Antigens; Autoimmune diseases; bone marrow‐derived dendritic cells; Cell Culture Techniques - methods; Chemical vapor deposition; Cytokines; Dendritic Cells - metabolism; Differentiation; functional polymer filmss; Growth factors; Hydrophobicity; initiated chemical vapor deposition (iCVD); Lymphocyte Activation; Lymphocytes; Modulation; Nanotechnology; Polymer films; Polymers; Polymers - metabolism; Substrates; Surface energy; type 1 conventional dendritic cells; surface energy; bone marrow-derived dendritic cells; functional polymer filmss; initiated chemical vapor deposition (iCVD); type 1 conventional dendritic cells

Although the dendritic cell (DC)‐based modulation of immune responses has emerged as a promising therapeutic strategy for tumors, infections, and autoimmune diseases, basic research and therapeutic applications of DCs are hampered by expensive growth factors and sophisticated culture procedures. Fur...