Asymmetric Sulfoxidation of Thioether Catalyzed by Soybean Pod Shell Peroxidase to Form Enantiopure Sulfoxide in Water‐in‐Oil Microemulsions: A Kinetic Model

• Published in: Chemistry, an Asian journal Vol. 16; no. 15; pp. 2075 - 2086
• Main Authors: Li, Huiling, Deng, Yashan, Du, ShanShan, Liu, Cui, Li, Kaiyuan, Xue, Xiao, Xu, Hui, Zhang, Yuanyuan, Yi, Tingting, Gao, Xin
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 02.08.2021
• Subjects: Asymmetric sulfoxidation; Asymmetry; Catalysis; Chemical reactions; Chemistry; Chiral sulfoxides; Electron transfer; Emulsions - chemistry; Glycine max - enzymology; Hydrogen peroxide; Kinetic model; Kinetics; Microemulsions; Models, Biological; Molecular Structure; Natural resources; Oils - chemistry; Oxidation; Peroxidase; Peroxidase - metabolism; Product inhibition; Reaction kinetics; Reaction mechanisms; Soybean pod shell peroxidase; Soybeans; Stereoisomerism; Substrate inhibition; Sulfides - chemistry; Sulfides - metabolism; Sulfoxides; Sulfoxides - chemistry; Sulfoxides - metabolism; Thermal stability; Water - chemistry; Kinetic model; Chiral sulfoxides; Substrate inhibition; Asymmetric sulfoxidation; Soybean pod shell peroxidase

Esomeprazole with chiral sulfoxides structure is used to treat gastric ulcer disease. Soybean pod shell peroxidase (SPSP) is a peroxidase extracted from soybean pods shells which are one of the most abundant natural resources in the world. In the production of chiral sulfoxides catalyzed by SPSP, it...