Exploring the Therapeutic Potential of Lawsone and Nanoparticles in Cancer and Infectious Disease Management

Lawsone, a naturally occurring compound found in henna, has been used in traditional medicine for centuries due to its diverse biological activities. In recent years, its nanoparticle‐based structure has gained attention in cancer and infectious disease research. This review explores the therapeutic...

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Published inChemistry & biodiversity Vol. 21; no. 4; pp. e202301777 - n/a
Main Authors Kamil Zaidan, Haider, Jasim Al‐Khafaji, Hanadi Had, Al‐dolaimy, F., Abed Hussein, Shaymaa, Otbah Farqad, Rand, Thabit, Daha, Talib Kareem, Ashwaq, Ramadan, Montather F., Hamood, Sarah A., Alawadi, Ahmed Hussien, Alsaalamy, Ali
Format Journal Article
LanguageEnglish
Published Switzerland Wiley Subscription Services, Inc 01.04.2024
Subjects
Anticancer
Anticancer properties
Antimicrobial activity
Apoptosis
Cancer
Cell proliferation
Clinical trials
Communicable Diseases
Disease Management
Effectiveness
Humans
Infection therapy
Infectious diseases
Lawsone
Medical research
Medical treatment
Nanomaterials
Nanoparticles
Naphthoquinones - chemistry
Neoplasms - drug therapy
Pathogens
Physicochemical processes
Physicochemical properties
Precision medicine
Proliferation
Nanomaterials
Infection therapy
Anticancer
Lawsone
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Abstract Lawsone, a naturally occurring compound found in henna, has been used in traditional medicine for centuries due to its diverse biological activities. In recent years, its nanoparticle‐based structure has gained attention in cancer and infectious disease research. This review explores the therapeutic potential of lawsone and its nanoparticles in the context of cancer and infectious diseases. Lawsone exhibits promising anticancer properties by inducing apoptosis and inhibiting cell proliferation, while its nanoparticle formulations enhance targeted delivery and efficacy. Moreover, lawsone demonstrates significant antimicrobial effects against various pathogens. The unique physicochemical properties of lawsone nanoparticles enable efficient cellular uptake and targeted delivery. Potential applications in combination therapy and personalized medicine open new avenues for cancer and infectious disease treatment. While clinical trials are needed to validate their safety and efficacy, lawsone‐based nanoparticles offer hope in addressing unmet medical needs and revolutionizing therapeutic approaches.
AbstractList Lawsone, a naturally occurring compound found in henna, has been used in traditional medicine for centuries due to its diverse biological activities. In recent years, its nanoparticle-based structure has gained attention in cancer and infectious disease research. This review explores the therapeutic potential of lawsone and its nanoparticles in the context of cancer and infectious diseases. Lawsone exhibits promising anticancer properties by inducing apoptosis and inhibiting cell proliferation, while its nanoparticle formulations enhance targeted delivery and efficacy. Moreover, lawsone demonstrates significant antimicrobial effects against various pathogens. The unique physicochemical properties of lawsone nanoparticles enable efficient cellular uptake and targeted delivery. Potential applications in combination therapy and personalized medicine open new avenues for cancer and infectious disease treatment. While clinical trials are needed to validate their safety and efficacy, lawsone-based nanoparticles offer hope in addressing unmet medical needs and revolutionizing therapeutic approaches.
Abstract Lawsone, a naturally occurring compound found in henna, has been used in traditional medicine for centuries due to its diverse biological activities. In recent years, its nanoparticle‐based structure has gained attention in cancer and infectious disease research. This review explores the therapeutic potential of lawsone and its nanoparticles in the context of cancer and infectious diseases. Lawsone exhibits promising anticancer properties by inducing apoptosis and inhibiting cell proliferation, while its nanoparticle formulations enhance targeted delivery and efficacy. Moreover, lawsone demonstrates significant antimicrobial effects against various pathogens. The unique physicochemical properties of lawsone nanoparticles enable efficient cellular uptake and targeted delivery. Potential applications in combination therapy and personalized medicine open new avenues for cancer and infectious disease treatment. While clinical trials are needed to validate their safety and efficacy, lawsone‐based nanoparticles offer hope in addressing unmet medical needs and revolutionizing therapeutic approaches.
Author Abed Hussein, Shaymaa
Alawadi, Ahmed Hussien
Ramadan, Montather F.
Al‐dolaimy, F.
Otbah Farqad, Rand
Hamood, Sarah A.
Thabit, Daha
Alsaalamy, Ali
Jasim Al‐Khafaji, Hanadi Had
Talib Kareem, Ashwaq
Kamil Zaidan, Haider
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Keywords Nanomaterials
Infection therapy
Anticancer
Lawsone
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Snippet Lawsone, a naturally occurring compound found in henna, has been used in traditional medicine for centuries due to its diverse biological activities. In recent...
Abstract Lawsone, a naturally occurring compound found in henna, has been used in traditional medicine for centuries due to its diverse biological activities....
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StartPage e202301777
SubjectTerms Anticancer
Anticancer properties
Antimicrobial activity
Apoptosis
Cancer
Cell proliferation
Clinical trials
Communicable Diseases
Disease Management
Effectiveness
Humans
Infection therapy
Infectious diseases
Lawsone
Medical research
Medical treatment
Nanomaterials
Nanoparticles
Naphthoquinones - chemistry
Neoplasms - drug therapy
Pathogens
Physicochemical processes
Physicochemical properties
Precision medicine
Proliferation
Title Exploring the Therapeutic Potential of Lawsone and Nanoparticles in Cancer and Infectious Disease Management
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fcbdv.202301777
https://www.ncbi.nlm.nih.gov/pubmed/38373183
https://www.proquest.com/docview/3039679803/abstract/
https://search.proquest.com/docview/2928856466
Volume 21
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