Low Dose of X‐Ray‐Excited Long‐Lasting Luminescent Concave Nanocubes in Highly Passive Targeting Deep‐Seated Hepatic Tumors

• Published in: Advanced materials (Weinheim) Vol. 31; no. 49; pp. e1905087 - n/a
• Main Authors: Chen, Zheng‐Zhe, Wang, Liu‐Chun, Manoharan, Divinah, Lee, Chin‐Lai, Wu, Lai‐Chin, Huang, Wan‐Ting, Huang, Eng‐Yen, Su, Chia‐Hao, Sheu, Hwo‐Shuenn, Yeh, Chen‐Sheng
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.12.2019
• Subjects: Animals; cancer; Chromium; Chromium - analysis; Dispersion; Excitation; Hep G2 Cells; Humans; Liver Neoplasms - diagnostic imaging; long‐lasting luminescence; Luminescence; Luminescent Agents - analysis; Luminescent Measurements - methods; Male; Materials science; Mice; Mice, Inbred C57BL; Morphology; Nanoparticles - analysis; Optical Imaging - methods; passive targeting; Phosphors; Tumors; X-Rays; Zinc - analysis; ZnGa2O4:Cr; cancer; passive targeting; ZnGa2O4:Cr; long-lasting luminescence; X-rays

Chromium‐doped zinc gallate, ZnGa2O4:Cr3+ (ZGC), is viewed as a long‐lasting luminescence (LLL) phosphor that can avoid tissue autofluorescence interference for in vivo imaging detection. ZGC is a cubic spinel structure, a typical agglomerative or clustered morphology lacking a defined cubic shape,...