Half‐Curcumin‐Based Chemiluminescence Probes and Their Applications in Detecting Quasi‐Stable Oxidized Proteins

• Published in: Angewandte Chemie International Edition Vol. 63; no. 40; pp. e202409896 - n/a
• Main Authors: Yang, Jun, Zhu, Biyue, Zhang, Jing, Liang, Steven H., Shen, Shiqian, Ran, Chongzhao
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 01.10.2024; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: Acetylacetone; Aging; Alzheimer's disease; Amino acids; Chemiluminescence; Chemistry; Chemistry, Multidisciplinary; Curcumin; Disease control; In vitro methods and tests; in vivo imaging; In vivo methods and tests; liquid biopsy; Neurodegenerative diseases; Physical Sciences; Proteins; Quasi-stable oxidized proteins; Reactive nitrogen species; Reactive oxygen species; Science & Technology; Taurine; ELECTROGENERATED CHEMILUMINESCENCE; in vivo imaging; OXIDATIVE STRESS; Quasi-stable oxidized proteins; chemiluminescence; ALZHEIMERS-DISEASE; HYPOCHLOROUS ACID; CROSS-LINKING; TAURINE CHLORAMINE; IRIDIUM(III) COMPLEXES; FREE-RADICAL THEORY; AMYLOID-BETA; HYDROGEN-PEROXIDE; liquid biopsy; curcumin
• ISSN: 1433-7851; 1521-3773; 1521-3773
• DOI: 10.1002/anie.202409896

Numerous methods have been reported for detecting ROS/RNS in vitro and in vivo; however, detecting methods for the secondary products of the reactive oxygen species (ROS)/reactive nitrogen species (RNS) reactions, particularly quasi‐stable oxidized products, have been much less explored. In this rep...