Tailor‐Made Polyhydroxyalkanoates by Reconstructing Pseudomonas Entomophila

• Published in: Advanced materials (Weinheim) Vol. 33; no. 41; pp. e2102766 - n/a
• Main Authors: Li, Mengyi, Ma, Yueyuan, Zhang, Xu, Zhang, Lizhan, Chen, Xinyu, Ye, Jian‐Wen, Chen, Guo‐Qiang
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.10.2021
• Subjects: Acyl Coenzyme A - metabolism; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Carbon; Copolymers; Fatty acids; Fatty Acids - metabolism; flux tuning; Glucose - metabolism; Hydroxybutyrates - chemistry; Hydroxybutyrates - metabolism; Mechanical properties; metabolic engineering; Microorganisms; Molecular chains; Monomers; Multigene Family; Oxidation; Oxidation-Reduction; Plasmids - genetics; Plasmids - metabolism; Polyesters - chemistry; Polyesters - metabolism; Polyhydroxyalkanoates; Polyhydroxyalkanoates - chemistry; Polyhydroxyalkanoates - metabolism; Pseudomonas; Pseudomonas - genetics; Pseudomonas - metabolism; Pseudomonas entomophila; SCL‐co‐LCL PHA copolymer; SCL‐co‐MCL PHA copolymer; Synthesis; synthetic biology; Thermodynamic properties; Weight; Pseudomonas entomophila; flux tuning; synthetic biology; SCL-co-LCL PHA copolymer; metabolic engineering; polyhydroxyalkanoates; SCL-co-MCL PHA copolymer

Microbial polyhydroxyalkanoates (PHA) containing short‐ and medium/long‐chain‐length monomers, abbreviated as SCL‐co‐MCL/LCL PHAs, generate suitable thermal and mechanical properties. However, SCL‐co‐MCL/LCL PHAs with carbon chain longer than nine are difficult to synthesize due to the low specifici...