A General Approach to Design Dual Ratiometric Fluorescent and Photoacoustic Probes for Quantitatively Visualizing Tumor Hypoxia Levels In Vivo - Zhang, Shuping; Chen, Hua; Wang, Liping; Qin, Xue; Jiang, Bang‐Ping; Ji, Shi‐Chen; Shen, Xing‐Can; Liang, Hong (Angewandte Chemie International Edition, 2022)
Keywords: Animals; Biomarkers; Breast cancer; Carbocyanines - chemical synthesis; Carbocyanines - chemistry; Cell Line, Tumor; Chemistry; Chemistry, Multidisciplinary; Drug Design; Dual ratiometric platform; Energy balance; Fluorescence; Fluorescent Dyes - chemical synthesis; Fluorescent Dyes - chemistry; Fluorescent indicators; Hypoxia; In vivo imaging; Mammary Neoplasms, Experimental - diagnostic imaging; Medical imaging; Mice; Mice, Nude; Molecular Structure; Nitrobenzene; Nitrogen dioxide; Nitroreductase; Optical Imaging; Photoacoustic effect; Photoacoustic Techniques; Physical Sciences; Quantitative detection; Scaffolds; Science & Technology; Solid tumors; Sulfur; Thioxanthene; Tumor Hypoxia; Tumors; Xenografts; Xenotransplantation; Dual ratiometric platform; NANOPARTICLES; Nitroreductase; Tumor hypoxia; AGENTS; MICROSCOPY; Quantitative detection; In vivo imaging; NEAR-INFRARED FLUORESCENCE