Development of “CLAN” Nanomedicine for Nucleic Acid Therapeutics

• Published in: Small (Weinheim an der Bergstrasse, Germany) Vol. 15; no. 16; pp. e1900055 - n/a
• Main Authors: Xu, Cong‐Fei, Iqbal, Shoaib, Shen, Song, Luo, Ying‐Li, Yang, Xianzhu, Wang, Jun
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.04.2019
• Subjects: cationic lipid assisted nanoparticles; Controllability; gene editing; Lipids; Macromolecules; nanomedicine; Nanoparticles; Nanotechnology; nucleic acid therapeutics; Nucleic acids; siRNA delivery; siRNA delivery; nanomedicine; cationic lipid assisted nanoparticles; gene editing; nucleic acid therapeutics

Nucleic acid‐based macromolecules have paved new avenues for the development of therapeutic interventions against a spectrum of diseases; however, their clinical translation is limited by successful delivery to the target site and cells. Therefore, numerous systems have been developed to overcome de...