Novel Antifungal and Antifeedant Metabolites from Penicillium chrysogenum Co‐Cultured with Nemania primolutea and Aspergillus fumigatus

• Published in: Chemistry & biodiversity Vol. 20; no. 4; pp. e202300004 - n/a
• Main Authors: Cen, Rong‐Huan, Li, Shi‐Yu, Yang, Ya‐Bin, Yang, Xue‐Qiong, Ding, Zhong‐Tao
• Format: Journal Article
• Language: English
• Published: Switzerland Wiley Subscription Services, Inc 01.04.2023
• Subjects: Antifungal agents; Antifungal Agents - chemistry; Antifungal Agents - metabolism; Antifungal Agents - pharmacology; Ascomycota - chemistry; Ascomycota - metabolism; Aspergillus fumigatus; Aspergillus fumigatus - chemistry; Aspergillus fumigatus - metabolism; Benzoic acid; bioactive metabolite; coculture; Culture Techniques - methods; Endophytes; Fungi; Fungicides; Metabolites; Nemania; Nemania primolutea; Penicillium - chemistry; Penicillium - metabolism; Penicillium chrysogenum; Penicillium chrysogenum - chemistry; Penicillium chrysogenum - metabolism; Silkworms; Yard waste; coculture; bioactive metabolite; Aspergillus fumigatus; Nemania primolutea; Penicillium chrysogenum

The endophyte Nemania primolutea, inhibited the growth of Penicillium chrysogenum in the coculture system. Four new compounds, nemmolutines A–B (1–2), and penigenumin (3) from N. primolutea, penemin (4) from P. chrysogenum were isolated from the coculture. On the other hand, P. chrysogenum inhibited...