Reactive Oxygen Species Suppressive Kraft Lignin‐Gelatin Antioxidant Hydrogels for Chronic Wound Repair

• Published in: Macromolecular bioscience Vol. 22; no. 11; pp. e2200234 - n/a
• Main Authors: Kim, Byulhana, Kim, Young, Lee, Yoonho, Oh, Joomin, Jung, Youngmee, Koh, Won‐Gun, Chung, Justin J.
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.11.2022
• Subjects: antioxidant hydrogel; Antioxidants; Antioxidants - pharmacology; Biocompatibility; chronic wound repair; Epichlorohydrin; Gelatin; Gelatin - pharmacology; Hydrogels; Hydrogels - pharmacology; Inflammation; Inflammatory response; kraft lignin; Lignin; Mechanical properties; Oxidative stress; Oxygen; Reactive oxygen species; reactive oxygen species (ROS); Reactive Oxygen Species - metabolism; Ring opening; Scavenging; Wound Healing; chronic wound repair; kraft lignin; reactive oxygen species (ROS); antioxidant hydrogel

Chronic wound is difficult to repair because the normal wound healing mechanism is inhibited by the continuous inflammatory response. The delayed inflammatory responses generate high level of reactive oxygen species (ROS) at the wound sites, which leads to a longer inflammatory phase and induces a v...