Assessing changes in facial skin quality using noninvasive in vivo clinical skin imaging techniques after use of a topical retinoid product in subjects with moderate‐to‐severe photodamage

• Published in: Skin research and technology Vol. 28; no. 4; pp. 604 - 613
• Main Authors: Goberdhan, Lisa T., Pellacani, Giovanni, Ardigo, Marco, Schneider, Katie, Makino, Elizabeth T., Mehta, Rahul C.
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.07.2022; John Wiley and Sons Inc
• Subjects: Aged; Antera 3D; Attenuation coefficients; Collagen; Confocal microscopy; cosmetic; Cosmetics; Epidermis; Evaluation; Face - diagnostic imaging; FACE‐Q; Fibers; Forehead; Humans; Image analysis; Image processing; Imaging techniques; In vivo methods and tests; Microscopy, Confocal - methods; Middle Aged; Optical Coherence Tomography; Original; photodamage; Photography; reflectance confocal microscopy; Retinoids; retinol; Roughness; Skin; Skin Aging; Stratum corneum; Stroma; Tomography, Optical Coherence - methods; Unevenness; Vitamin A; reflectance confocal microscopy; retinol; Antera 3D; optical coherence tomography; FACE-Q; cosmetic; photodamage

Background Studies utilizing reflectance confocal microscopy (RCM) and dynamic optical coherence tomography (D‐OCT) to assess cosmetic skin changes are limited. Methods A 12‐week, open‐label study was conducted using RCM and D‐OCT to evaluate the effects of a topical cosmetic retinol (RET05) on subj...