Structure Engineering of a Lanthanide‐Based Metal–Organic Framework for the Regulation of Dynamic Ranges and Sensitivities for Pheochromocytoma Diagnosis

• Published in: Advanced materials (Weinheim) Vol. 32; no. 23; pp. e2000791 - n/a
• Main Authors: Hao, Ji‐Na, Niu, Dechao, Gu, Jinlou, Lin, Shaoliang, Li, Yongsheng, Shi, Jianlin
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.06.2020
• Subjects: Adrenal Gland Neoplasms - diagnosis; Adrenal Gland Neoplasms - urine; Animals; Biomolecules; Biosensing Techniques; Biosensors; Cell Line, Tumor; Diagnosis; Engineering; Europium - chemistry; Humans; Materials science; Metal-organic frameworks; Metal-Organic Frameworks - chemistry; Mice; Pheochromocytoma - diagnosis; Pheochromocytoma - urine; tailorable structures; Target detection; tunable biosensors; vanillylmandelic acid; Vanilmandelic Acid - urine; tunable biosensors; tailorable structures; vanillylmandelic acid; pheochromocytoma diagnosis; metal-organic frameworks
• ISSN: 0935-9648; 1521-4095; 1521-4095
• DOI: 10.1002/adma.202000791

Exploring innovative technologies to precisely quantify biomolecules is crucial but remains a great challenge for disease diagnosis. Unfortunately, the humoral concentrations of most biotargets generally vary within rather limited scopes between normal and pathological states, while most literature‐...