Drug Delivery to the Brain across the Blood–Brain Barrier Using Nanomaterials

• Published in: Small (Weinheim an der Bergstrasse, Germany) Vol. 13; no. 43
• Main Authors: Tsou, Yung‐Hao, Zhang, Xue‐Qing, Zhu, He, Syed, Sahla, Xu, Xiaoyang
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.11.2017
• Subjects: Alzheimer's disease; Blood-brain barrier; Brain diseases; Circulatory system; drug delivery; Drug delivery systems; Functional groups; Multiple sclerosis; Nanomaterials; Nanotechnology; blood brain barrier; nanotechnology; drug delivery

A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis, brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of certain molecules and pathogens from the circulatory system into the brain. Therefore, it is nearly impossible for...