Spermine‐Responsive Intracellular Self‐Aggregation of Gold Nanocages for Enhanced Chemotherapy and Photothermal Therapy of Breast Cancer

• Published in: Small (Weinheim an der Bergstrasse, Germany) Vol. 18; no. 30; pp. e2201971 - n/a
• Main Authors: Xie, Beibei, Zhao, Huichao, Shui, Mingju, Ding, Yuan‐Fu, Sun, Chen, Wang, Ziyi, Gao, Cheng, Chen, Guosong, Wang, Ruibing
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.07.2022
• Subjects: Accumulation; Agglomeration; Au nanocages; Breast cancer; cancer therapy; Chemotherapy; Clusters; cucurbituril; Doxorubicin; Esterification; Nanotechnology; Peptides; Photothermal conversion; Retention; self‐aggregation; stimuli‐responsive; Tumors; cancer therapy; cucurbituril; stimuli-responsive; self-aggregation; Au nanocages

Improving the precise accumulation and retention of nanomedicines in tumor cells is one of the keys to effective therapy of tumors. Herein, supramolecular peptides capped Au nanocages (AuNCs) that may self‐aggregate into micron‐sized clusters intracellularly in response to spermine (SPM), leading to...