Neutrophil and Nanoparticles Delivery to Tumor: Is It Going to Carry That Weight?

• Published in: Advanced healthcare materials Vol. 10; no. 9; pp. e2002071 - n/a
• Main Authors: Vishnevskiy, Daniil A., Garanina, Anastasiia S., Chernysheva, Anastasia A., Chekhonin, Vladimir P., Naumenko, Victor A.
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.05.2021
• Subjects: Antitumor activity; cell‐based delivery; Drug delivery; endocytosis; Internalization; Leukocytes (neutrophilic); Nanoparticles; Neutrophils; Tumors; endocytosis; cell-based delivery; tumors; nanoparticles; neutrophils

The application of cell carriers for transporting nanodrugs to the tumor draws much attention as the alternative to the passive drug delivery. In this concept, the neutrophil (NΦ) is of special interest as this cell is able to uptake nanoparticles (NPs) and cross the vascular barrier in response to...