Design, Synthesis, and Evaluation of Chalcone Derivatives as Multifunctional Agents against Alzheimer's Disease - Wang, Xiao‐Qin; Zhou, Lu‐Yi; Tan, Ren‐Xian; Liang, Guo‐Peng; Fang, Si‐Xian; Li, Wei; Xie, Mei; Wen, Yu‐Hao; Wu, Jia‐Qiang; Chen, Yi‐Ping (Chemistry & biodiversity, 2021)
Keywords: Agglomeration; Alzheimer Disease - drug therapy; Alzheimer Disease - metabolism; Alzheimer's disease; Amyloid beta-Peptides - antagonists & inhibitors; Amyloid beta-Peptides - metabolism; Animals; Antioxidants; Aβ aggregation; Cell Survival - drug effects; chalcone; Chalcones - chemical synthesis; Chalcones - chemistry; Chalcones - pharmacology; Chelation; Copper; Copper - pharmacology; Cytotoxicity; Drug Design; Fibrils; Humans; Memory Disorders - chemically induced; Memory Disorders - drug therapy; metal chelating; Mice; multifunctional; Neurodegenerative diseases; Neuroprotective Agents - chemical synthesis; Neuroprotective Agents - chemistry; Neuroprotective Agents - pharmacology; Peptide Fragments - antagonists & inhibitors; Peptide Fragments - metabolism; Protein Aggregates - drug effects; Scopolamine; Toxicity; Tumor Cells, Cultured; chalcone; Aβ aggregation; multifunctional; Alzheimer's disease; metal chelating