Tumor‐Selective Nano‐Dispatcher Enforced Cancer Immunotherapeutic Effects via Regulating Lactate Metabolism and Activating Toll‐Like Receptors - Liu, Yang; Li, Hui; Hao, Yan‐Yun; Huang, Ling‐Ling; Li, Xia; Zou, Jing; Zhang, Shi‐Ying; Yang, Xiao‐Yue; Chen, Hong‐Fei; Guo, Yi‐Xuan; Guan, Yun‐Yan; Zhang, Zhi‐Yue (Small (Weinheim an der Bergstrasse, Germany), 2025)
Keywords: Accumulation; Acidosis; Animals; Anticancer properties; Cell Line, Tumor; Efflux; Humans; Immune system; immune therapy; Immunotherapy - methods; lactate metabolism; Lactic Acid - chemistry; Lymphocytes; Metabolism; Mice; monocarboxylate transporters 4 (MCT4); Monocarboxylic Acid Transporters - antagonists & inhibitors; Monocarboxylic Acid Transporters - metabolism; Nanoparticles - chemistry; nano‐dispatcher; Neoplasms - immunology; Neoplasms - metabolism; Neoplasms - pathology; Neoplasms - therapy; Proteins; Receptors; TLR7/8; Toll-Like Receptors - metabolism; Tumor Microenvironment - drug effects; lactate metabolism; immune therapy; nano‐dispatcher; TLR7/8; monocarboxylate transporters 4 (MCT4)