Multi-Timepoint Metabolic Fingerprinting of a Post-Episode Period of Hypoglycemia and Ketoacidosis Among Children With Type 1 Diabetes

• Published in: Frontiers in molecular biosciences Vol. 9; p. 869116
• Main Authors: Małachowska, Beata, Pietrowska, Karolina, Młynarski, Wojciech, Szadkowska, Agnieszka, Krętowski, Adam, Ciborowski, Michał, Fendler, Wojciech
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 23.06.2022
• Subjects: diabetes ketoacidosis (DKA); hypoglycemia; LC-MS; metabolomics; Molecular Biosciences; serum; type 1 diabetes

Background: Acute complications of type 1 diabetes mellitus such as diabetes ketoacidosis (DKA) and hypoglycemia (HG) are detrimental in a short- and long-term perspective. Restoration of normoglycemia and correction of pH do not mean that all metabolic disturbances caused by HG or DKA are immediate...