The role of zinc and its compounds in leukemia

• Published in: Journal of biological inorganic chemistry Vol. 23; no. 3; pp. 347 - 362
• Main Authors: Orlov, Alexey P., Orlova, Marina A., Trofimova, Tatiana P., Kalmykov, Stepan N., Kuznetsov, Dmitry A.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2018; Springer Nature B.V
• Subjects: Binding Sites; Biochemistry; Biomedical and Life Sciences; Conformation; Homeostasis; Humans; Inorganic chemistry; Leukemia; Leukemia - drug therapy; Leukemia - metabolism; Life Sciences; Microbiology; Minireview; Transcription factors; Transcription Factors - metabolism; Zinc; Zinc - chemistry; Zinc - metabolism; Zinc - therapeutic use; Zinc Compounds - chemistry; Zinc Compounds - metabolism; Zinc Compounds - therapeutic use; Zinc salicylates; Signaling pathway; Zinc chelation; Zinc complexes; Zinc fingers; Zinc; Metallothioneins

Zinc is one of the most important microelements necessary for normal body functioning. Zinc is marked in numerous diseases and, hence, its properties and behavior in the body have long been a subject of extensive study. This review considers trends in the assessment of the role of zinc and its compo...