Brainstem reflexes are hyperactive in patients with drug-induced akathisia

• Published in: Neurological sciences Vol. 38; no. 9; pp. 1683 - 1689
• Main Authors: Metin, Baris, Metin, Sinem Zeynep, Gunduz, Aysegul, Poyraz, Burc Cagri, Ozmen, Mine, Kiziltan, Gunes, Kiziltan, Meral E.
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 01.09.2017; Springer Nature B.V
• Subjects: Amygdala; Brain stem; Dopamine receptors; Flexor reflex; Forebrain; Hyperactivity; Latency; Medicine; Medicine & Public Health; Motor task performance; Neurology; Neuroradiology; Neurosciences; Neurosurgery; Original Article; Pain perception; Psychiatry; Reflexes; Restless legs syndrome; Sensorimotor integration; Startle response; Startle reflex to somatosensory inputs; Reticulospinal tract; Auditory startle reflex; Dopaminergic pathways; Trigemino-cervical reflex; Drug-induced akathisia

Akathisia is a sensori-motor phenomenon which is generally encountered as an adverse effect of antidopaminergic medications suggesting involvement of dopaminergic pathways. We recently showed nociceptive flexor reflex was altered in akathisia as compared to restless legs syndrome and therefore, thes...