Recent Selection on Synonymous Codon Usage in Drosophila

• Published in: Journal of molecular evolution Vol. 49; no. 3; pp. 343 - 351
• Main Author: Kliman, Richard M.
• Format: Journal Article
• Language: English
• Published: Germany Springer Nature B.V 01.09.1999
• Subjects: alcohol dehydrogenase; Animals; Coalescence; Codon; Codon - genetics; codons; Drosophila; Drosophila - genetics; Drosophila melanogaster; Drosophila melanogaster - genetics; Drosophila simulans; esterase; esterases; Evolution, Molecular; Evolutionary biology; Frequency distribution; Genes, Insect; genetic code; genetics; Insects; interspecific variation; loci; Models, Genetic; natural selection; Polymorphism; Population genetics; Simulation
• ISSN: 0022-2844; 1432-1432
• DOI: 10.1007/PL00006557

Evidence from a variety of sources indicates that selection has influenced synonymous codon usage in Drosophila. It has generally been difficult, however, to distinguish selection that acted in the distant past from ongoing selection. However, under a neutral model, polymorphisms usually reflect mor...