Multiparametric PET/MR imaging biomarkers are associated with overall survival in patients with pancreatic cancer

• Published in: European journal of nuclear medicine and molecular imaging Vol. 45; no. 7; pp. 1205 - 1217
• Main Authors: Chen, Bang-Bin, Tien, Yu-Wen, Chang, Ming-Chu, Cheng, Mei-Fang, Chang, Yu-Ting, Yang, Shih-Hung, Wu, Chih-Horng, Kuo, Ting-Chun, Shih, I-Lun, Yen, Ruoh-Fang, Shih, Tiffany Ting-Fang
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2018; Springer Nature B.V
• Subjects: Aged; Biomarkers; Cancer; Cardiology; Choline; Diffusion coefficient; Female; Fluorine; Fluorodeoxyglucose F18; Glycolysis; Humans; Imaging; Informed consent; Magnetic Resonance Imaging; Magnetic resonance spectroscopy; Male; Medical imaging; Medicine; Medicine & Public Health; Metabolism; Middle Aged; Multivariate analysis; NMR; Nuclear magnetic resonance; Nuclear Medicine; Oncology; Original Article; Orthopedics; Pancreatic cancer; Pancreatic Neoplasms - diagnostic imaging; Pancreatic Neoplasms - mortality; Patients; Positron emission; Positron emission tomography; Prognosis; Prospective Studies; Radiology; Radiopharmaceuticals; Retrospective Studies; Subgroups; Surgery; Survival; Tomography; Tumor Burden; Tumors; Diffusion weighted MRI; Dynamic contrast-enhanced MRI; PET/MR; Overall survival; Pancreatic cancer; MR spectroscopy

Purpose To correlate the overall survival (OS) with the imaging biomarkers of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), diffusion-weighted imaging (DWI), magnetic resonance spectroscopy, and glucose metabolic activity derived from integrated fluorine 18 fluorodeoxyglucose posit...