The role of intermediate filaments in maintaining integrity and function of intestinal epithelial cells after massive bowel resection in a rat

• Published in: Pediatric surgery international Vol. 34; no. 2; pp. 217 - 225
• Main Authors: Sukhotnik, I., Shahar, Y. Ben, Pollak, Y., Dorfman, T., Shefer, H. Kreizman, Assi, Z. E., Mor-Vaknin, N., Coran, A. G.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2018; Springer Nature B.V
• Subjects: Apoptosis; Cytoskeleton; Gene expression; Medicine; Medicine & Public Health; Original Article; Pediatric Surgery; Pediatrics; Rodents; Surgery; Vimentin; Cytoskeleton; Short bowel syndrome; Cell turnover; Intermediate filaments; Desmin

Purpose Intermediate filaments (IFs) are a part of the cytoskeleton that extend throughout the cytoplasm of all cells and function in the maintenance of cell-shape by bearing tension and serving as structural components of the nuclear lamina. In normal intestine, IFs provide a tissue-specific three-...