Green synthesized ZnO nanosheets from banana peel extract possess anti-bacterial activity and anti-cancer activity

• Published in: Materials today communications Vol. 24; p. 101224
• Main Authors: Ruangtong, Jittiporn, T-Thienprasert, Jiraroj, T-Thienprasert, Nattanan Panjaworayan
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.09.2020
• Subjects: Anti-bacterial activity; Anti-cancer activity; Banana peel extract; Green synthesis; Zinc acetate; Zinc oxide nanoparticle; Zinc oxide nanoparticle; Green synthesis; Zinc acetate; Banana peel extract; Anti-bacterial activity; Anti-cancer activity
• ISSN: 2352-4928; 2352-4928
• DOI: 10.1016/j.mtcomm.2020.101224

[Display omitted] •Banana peel crude extract acts as reducing and capping agents.•Increase concentration of precursor affected yield and size of ZnO nanomaterials.•Higher concentration of extract affected shape and purity of ZnO nanomaterials.•The green synthesized ZnO nanosheets possessed anti-bacterial activity.•The green synthesized ZnO nanosheets exhibited anti-cancer activity. Recently, green synthesis of metal oxide nanoparticles has gained extensive attention because it is an environment-friendly and cost-effective approach. This study therefore focused on green synthesis of zinc oxide nanoparticles (ZnO NPs) by using waste material, banana peel crude extract, as reducing as well as capping agents in the reaction with zinc acetate. The synthesized ZnO NPs with the average electronic band gap ∼3 eV were obtained and found to have rod-like or sheet-like structures depended on concentration of crude extract used in the reaction. By performing antibacterial activity assay, these green synthesized ZnO nanosheets inhibited growth of gram-positive bacteria, Bacillus subtilis, Staphylococcus epidermidis and gram-negative bacterium, Escherichia coli. Moreover, the synthesized ZnO nanosheets demonstrated potent anti-cancer activity against cell viability of skin cancer cell (A431), colorectal cancer cell (SW620) and liver cancer cell (HepG2) without affecting normal cell line (Vero). Therefore, these studies firstly reported potential usage of the green-synthesized ZnO nanosheets for development of anti-bacterial substances or anticancer drugs. Moreover, this study showed the opportunity to increase values of agricultural waste.