Teriparatide versus low-dose bisphosphonates before and after surgery for adult spinal deformity in female Japanese patients with osteoporosis

• Published in: European spine journal Vol. 26; no. 8; pp. 2121 - 2127
• Main Authors: Seki, Shoji, Hirano, Norikazu, Kawaguchi, Yoshiharu, Nakano, Masato, Yasuda, Taketoshi, Suzuki, Kayo, Watanabe, Kenta, Makino, Hiroto, Kanamori, Masahiko, Kimura, Tomoatsu
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2017; Springer Nature B.V
• Subjects: Aged; Aged, 80 and over; Bisphosphonates; Bone Density Conservation Agents - therapeutic use; Computed tomography; Diphosphonates - therapeutic use; Drug Administration Schedule; Female; Females; Fractures; Humans; Medicine; Medicine & Public Health; Middle Aged; Neurosurgery; Original Article; Osteoporosis; Osteoporosis, Postmenopausal - complications; Osteoporosis, Postmenopausal - drug therapy; Pain; Parathyroid hormone; Perioperative Care - methods; Prospective Studies; Spinal Curvatures - etiology; Spinal Curvatures - surgery; Surgery; Surgical Orthopedics; Teriparatide - therapeutic use; Treatment Outcome; Vertebrae; Teriparatide/TU bisphosphonates; Orthopedic procedures/AE; Osteoporosis/SU; Disability evaluation

Purpose Complications of adult spinal deformity surgery are problematic in osteoporotic individuals. We compared outcomes between Japanese patients treated perioperatively with teriparatide vs. low-dose bisphosphonates. Methods Fifty-eight osteoporotic adult Japanese female patients were enrolled an...