An ompR-envZ Two-Component System Ortholog Regulates Phase Variation, Osmotic Tolerance, Motility, and Virulence in Acinetobacter baumannii Strain AB5075

• Published in: Journal of bacteriology Vol. 199; no. 3; p. E00705
• Main Authors: Tipton, Kyle A., Rather, Philip N.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.02.2017
• Subjects: Acinetobacter; Acinetobacter baumannii; Bacteriology; Galleria mellonella; Genotype & phenotype; Gram-negative bacteria; Kinases; Motility; Mutation; Opacity; Osmosis; Protein folding; Sodium chloride; osmotic stress; Acinetobacter; phase variation

Recently, a novel phase-variable colony opacity phenotype was discovered in Acinetobacter baumannii strain AB5075, where colonies interconvert between opaque and translucent variants. Opaque colonies become mottled or sectored after 24 h of growth due to translucent variants arising within the colon...