Comprehensive analysis of miRNA-gene regulatory network with clinical significance in human cancers

• Published in: Science China. Life sciences Vol. 63; no. 8; pp. 1201 - 1212
• Main Authors: Cui, Xiuliang, Liu, Yang, Sun, Wen, Ding, Jin, Bo, Xiaochen, Wang, Hongyang
• Format: Journal Article
• Language: English
• Published: Beijing Science China Press 01.08.2020; Springer Nature B.V
• Subjects: Biomarkers; Biomedical and Life Sciences; Cancer; Clinical significance; DNA methylation; Drug development; Life Sciences; MicroRNAs; miRNA; mRNA; Research Paper; Therapeutic applications; exosomal miRNA; biomarker; clinical significance; prognosis; TCGA

microRNAs (miRNAs), particularly the exosomal miRNAs have been widely used as biomarkers and promising therapeutic targets in cancer. However, a comprehensive analysis of miRNA-gene regulatory network with clinical significance remains scarce. The emergence of high-throughput multi-omics data over l...