CAROTENOID CLEAVAGE DIOXYGENASE4 Is a Negative Regulator of β-Carotene Content in Arabidopsis Seeds

• Published in: The Plant cell Vol. 25; no. 12; pp. 4812 - 4826
• Main Authors: Gonzalez-Jorge, Sabrina, Ha, Sun-Hwa, Magallanes-Lundback, Maria, Gilliland, Laura Ullrich, Zhou, Ailing, Lipka, Alexander E., Nguyen, Yen-Nhu, Angelovici, Ruthie, Lin, Haining, Cepela, Jason, Little, Holly, Buell, C. Robin, Gore, Michael A., DellaPenna, Dean
• Format: Journal Article
• Language: English
• Published: England American Society of Plant Biologists 01.12.2013
• Subjects: Alleles; Arabidopsis - enzymology; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Arabidopsis Proteins - physiology; beta Carotene - biosynthesis; Carotenoids; Cellular Senescence; Chromosome Mapping; Dioxygenases - genetics; Dioxygenases - metabolism; Dioxygenases - physiology; Enzymes; Genetic loci; Genetic variation; Haplotypes; Homeostasis; Large-Scale Biology; LARGE-SCALE BIOLOGY ARTICLE; Mutagenesis, Insertional; Plant cells; Plant Leaves - metabolism; Plant Proteins - genetics; Plant Proteins - metabolism; Plant Proteins - physiology; Plants; Plants, Genetically Modified - metabolism; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Seeds; Seeds - genetics; Seeds - metabolism; Sequence Deletion

Experimental approaches targeting carotenoid biosynthetic enzymes have successfully increased the seed β-carotene content of crops. However, linkage analysis of seed carotenoids in Arabidopsis thaliana recombinant inbred populations showed that only 21% of quantitative trait loci, including those fo...